Phosphodiesterase 9 (PDE9) Inhibitors May Provide Effective Treatments for Neurodegenerative, Cardiovascular and Other Diseases. [PDF]
ACS Med Chem LettAbdel-Magid AF.
europepmc +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar +6 more
wiley +1 more source
Pan-Cancer Analysis of Cyclic Nucleotide Phosphodiesterases (PDEs) Expression, Variation, and Prognostic Significance. [PDF]
ACS OmegaWu Z, Ren H, Guo F.
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Computing Skinning Weights via Convex Duality
Computer Graphics Forum, EarlyView.We present an alternate optimization method to compute bounded biharmonic skinning weights. Our method relies on a dual formulation, which can be optimized with a nonnegative linear least squares setup. Abstract We study the problem of optimising for skinning weights through the lens of convex duality.
J. Solomon, O. Stein
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A novel shifted Vieta-Lucas spectral collocation approach for multidimensional generalized Benjamin-Bona-Mahony-Burgers equations. [PDF]
Sci RepHafez RM +4 more
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SDFs from Unoriented Point Clouds using Neural Variational Heat Distances
Computer Graphics Forum, EarlyView.We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from unoriented point clouds. We first compute a small time step of heat flow (middle) and then use its gradient directions to solve for a neural SDF (right). Abstract We propose a novel variational approach for computing neural Signed Distance Fields (SDF) from ...
Samuel Weidemaier +5 more
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EGaIn-Activated Bioinspired Silk Micro/Nanofibril Eutectogels Breaking the Strength-Conductivity Trade-Off for High-Performance Wearable Bioelectronics. [PDF]
Adv Sci (Weinh)Yang H, Ye D, You Y, Fu M, Wang Z.
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Controllable Intrinsic Surface Pattern Generation Using Slime Mold Simulations
Computer Graphics Forum, EarlyView.Abstract Surface‐based pattern simulations have proven valuable for texture design and scientific visualization, but existing methods face several limitations. Most simulations either target a narrow range of pattern types (e.g. spots, branching) or support a broad range of patterns at the cost of time‐consuming parameter tuning.
Jeffrey Layton +2 more
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Diffusion-Shock PDEs for Deep Learning on Position-Orientation Space. [PDF]
J Math Imaging VisSherry FM, Schaefer K, Duits R.
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Mesh Processing Non‐Meshes via Neural Displacement Fields
Computer Graphics Forum, EarlyView.Abstract Mesh processing pipelines are mature, but adapting them to newer non‐mesh surface representations—which enable fast rendering with compact file size—requires costly meshing or transmitting bulky meshes, negating their core benefits for streaming applications.
Yuta Noma +4 more
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