Results 51 to 60 of about 16,016 (265)

Cyclic AMP control measured in two compartments in HEK293 cells: phosphodiesterase K(M) is more important than phosphodiesterase localization. [PDF]

PLoS ONE, 2011
The intracellular second messenger cyclic AMP (cAMP) is degraded by phosphodiesterases (PDE). The knowledge of individual families and subtypes of PDEs is considerable, but how the different PDEs collaborate in the cell to control a cAMP signal is still ...
Karina Matthiesen, Jacob Nielsen
doaj   +1 more source

Radiative Hybrid Nanofluid Flow Over a Porous Riga Surface: A Fuzzy–ANN Modeling Approach

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a fuzzy–ANN model to investigate the nonlinear thermal transport in a tangent hyperbolic (Tanh) hybrid nanofluid flow past a porous Riga surface, considering the effects of Rosseland diffusion, chemical reactions, and internal volumetric heating.
Azad Hussain, Rabia Zetoon, Reeha Iqbal
wiley   +1 more source

Modified plant‐derived exosomes: Precision medicine in cancer treatment

Clinical and Translational Discovery
Plant‐derived exosomes (PDEs) are extracellular vesicles (EVs) occurring naturally,which have propitious applications in the development of cost‐effective and fruitful cancer therapy with minimum aftereffects and ramifications.
Swastika Maitra, Subham Sarkar, Bikram Dhara   +2 more
doaj   +1 more source

Pencil It in: Exploring the Feasibility of Hand-Drawn Pencil Electrochemical Sensors and Their Direct Comparison to Screen-Printed Electrodes

Biosensors, 2016
We explore the fabrication, physicochemical characterisation (SEM, Raman, EDX and XPS) and electrochemical application of hand-drawn pencil electrodes (PDEs) upon an ultra-flexible polyester substrate; investigating the number of draws (used for their ...
Elena Bernalte, Christopher W. Foster, Dale A.C. Brownson, Morgane Mosna, Graham C. Smith, Craig E. Banks   +5 more
doaj   +1 more source

Residual Strength Prediction of Chemically Reactive Two‐Phase Nanofluid Flow in a Bingham–Papanastasiou Rheological Theory Using a Morlet‐Based Wavelet Neural Network Approach

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The behavior of nanofluid flow involving a zero‐mass flux condition has received considerable interest because of a realistic scenario. In reality, this condition confines the optimistic accumulation or disappearance of nanoparticles past a sheet, constructing a more physically realistic demonstration through several applications, such as heat
Umair Khan, Hamza Rauf, Aurang Zaib, J. K. Madhukesh   +3 more
wiley   +1 more source

Least Squares Approximation of Flatness on Riemannian Manifolds

Mathematics, 2020
The purpose of this paper is fourfold: (i) to introduce and study the Euler–Lagrange prolongations of flatness PDEs solutions (best approximation of flatness) via associated least squares Lagrangian densities and integral functionals on Riemannian ...
Iulia Hirica, Constantin Udriste, Gabriel Pripoae, Ionel Tevy   +3 more
doaj   +1 more source

PDEs with compressed solutions [PDF]

Communications in Mathematical Sciences, 2015
Sparsity plays a central role in recent developments in signal processing, linear algebra, statistics, optimization, and other fields. In these developments, sparsity is promoted through the addition of an $L^1$ norm (or related quantity) as a constraint or penalty in a variational principle.
Caflisch, Russel E., Osher, Stanley J., Schaeffer, Hayden, Tran, Giang   +3 more
openaire   +3 more sources

Streamline and Isotherm Visual Analysis of Darcy–Forchheimer von Karman Spinning Flow of Maxwell Fluid Over a Stretching Disk With Quadratic Temperature‐Dependent Heat Source

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This research paper provides an extensive study of the effects of Darcy–Forchheimer von‐Karman spinning flow of Maxwell fluid across a stretching disk including the effect of heat generation based on a nonlinear function of temperature. The flow system is influenced by thermal radiations and Arrhenius activation energy.
Ebrahem A. Algehyne, Mounirah Areshi, Fahad Maqbul Alamrani, Zehba Raizah, Mustafa Bayram, Jihad Younis, Anwar Saeed   +6 more
wiley   +1 more source

Analysing detection of chronic diseases with prolonged sub-clinical periods: modelling and application to hypertension in the U.S.

BMC Medical Research Methodology, 2019
Background We recently introduced a system of partial differential equations (PDEs) to model the prevalence of chronic diseases with a possibly prolonged state of asymptomatic, undiagnosed disease preceding a diagnosis.
Ralph Brinks, Sophie Kaufmann, Annika Hoyer, Edward W Gregg, Jürgen Saal   +4 more
doaj   +1 more source

Phosphodiesterase and psychiatric disorders: a two-sample Mendelian randomization study

Journal of Translational Medicine, 2023
Background Phosphodiesterases (PDEs) have been associated with psychiatric disorders in observational studies; however, the causality of associations remains unestablished.
Miaomiao Jiang, Weiheng Yan, Yuyanan Zhang, Zhe Lu, Tianlan Lu, Dai Zhang, Jun Li, Lifang Wang   +7 more
doaj   +1 more source