Results 131 to 140 of about 166,339,283 (190)

Assessing the therapeutic potential of PDE‐5 inhibitors in adults: Insights from a multi‐omics study

Physiological Reports, Volume 14, Issue 18, September 2026.
Abstract Phosphodiesterase‐5 inhibitors have beneficial pleiotropic effects and hold promise as adjuvant treatments for cancer, dementia, and other disorders. Sixteen men and women aged 50–60 were administered daily sildenafil/tadalafil for 1 month. We characterized molecular signatures of sildenafil/tadalafil treatment via analyses and multi‐omics ...
Kristen A. McGovern, Traver J. Wright, Erik D. Marchant, Sean P. Kilroe, William J. Durham, E. Lichar Dillon, Marc M. Baum, Michael P. Kinsky, William K. Russell, Christopher S. Fry, Pratik Gongloor, Richard B. Pyles, Randall J. Urban, Blake B. Rasmussen, Melinda Sheffield‐Moore   +14 more
wiley   +1 more source

Riccati-based analytical framework for solving the potential Korteweg-de Vries equation. [PDF]

Sci Rep
Jawarneh Y, Mukhtar S, Islam S, Amadou Y.   +3 more
europepmc   +1 more source

Fully Coupled Electromagnetic‐Thermal‐Mechanical Model for Induction Heating of Thin Steel Sheets With the Presence of Thermal Buckling

International Journal for Numerical Methods in Engineering, Volume 127, Issue 16, 30 August 2026.
ABSTRACT Large deformations can become an important issue in induction heating applications, especially for structures with low bending stiffness, such as thin sheets. In such cases, thermal expansion induces not only substantial in‐plane stresses but also out‐of‐plane buckling, which in turn strongly influences the electromagnetic field configuration.
Vladimir Filkin, Yury Vetyukov, Florian Toth   +2 more
wiley   +1 more source

Fast automated adjoints for spectral PDE solvers. [PDF]

Proc Natl Acad Sci U S A
Skene CS, Burns KJ.
europepmc   +1 more source

Serum N-terminal Pro-B-Type Natriuretic Peptide and Phosphodiesterase 4D Levels in Adults With Overt Hypothyroidism: A Case-Control Study. [PDF]

Cureus
Amir SH, Zafar KS, Sharma I, Shafiq Siddiqi S.   +3 more
europepmc   +1 more source

Thermal Performance of ternary hybrid nanofluid with activation energy and surface tension gradient using HCM and YOM models. [PDF]

Discov Nano
Ettoumi M, Safra I, Secer A, Rakhmonov F, Kanwal S.   +4 more
europepmc   +1 more source

Phosphodiesterase 8 regulation of excitation-contraction coupling as a target for cardiovascular disease: is it my turn now? [PDF]

Am J Physiol Heart Circ Physiol
Xu (许莹) Y, McConnell BK.
europepmc   +1 more source

The Cyclic Adenosine Monophosphate Phosphodiesterase CpdA Modulates cAMP Homeostasis, Stress Adaptability, Biofilm Formation, Motility, Quorum Sensing and Antibiotic Resistance of <i>Aeromonas veronii</i>. [PDF]

J Microbiol Biotechnol
Yang W, Wang X, Zhou S, Yu G, Zhou X, Sui Z.   +5 more
europepmc   +1 more source

Cyclic AMP compartmentalization drives signal specificity to control vector colonization and mammalian host infection by American trypanosomes. [PDF]

PLoS Pathog
Ahmed M, Carlson J, Das A, Hoque SF, Benoit JB, Chiurillo MA, Lander N.   +6 more
europepmc   +1 more source

Phosphodiesterase signaling in asthma: mechanistic insights and emerging therapeutic strategies. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Alnusayri A, Al-Kuraishy HM, Alexiou A, Papadakis M, Faheem SA, Alruwaili M, Batiha GE.   +6 more
europepmc   +1 more source