Results 51 to 60 of about 3,082 (143)

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

The FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott, Jui‐Hung Weng, Valeria Pane, Yuliang Ma, Jian Wu, Susan S. Taylor, Friedrich W. Herberg   +6 more
wiley   +1 more source

Comparative analysis of canonical and noncanonical rhodopsins in Amphidinium carterae and Karlodinium veneficum

Journal of Phycology, EarlyView.
Abstract Rhodopsins are ancient and versatile light‐sensitive proteins, widely distributed across microbial life. In dinoflagellates, however, their diversity and function remain poorly understood, owing to the lineage's extreme genomic divergence. Here, we surveyed the rhodopsin complements of two dinoflagellates, Amphidinium carterae and Karlodinium ...
Jens Wira, Miranda Judd, Anne Baldino, Tsvetan Bachvaroff, Allen R. Place   +4 more
wiley   +1 more source

The Arabidopsis NPF7.2 mediates coumarin uptake for root iron acquisition

New Phytologist, EarlyView.
Summary Iron (Fe) is a transition metal necessary for achieving essential physiological processes throughout the plant lifecycle. In Arabidopsis thaliana, secreting Fe‐mobilizing coumarins (FMC) is a key mechanism enabling roots to acquire nonbioavailable Fe present in soils.
Shunsuke Watanabe, Meijie Li, Alice Rossille, Chérhazad Boustani, Kevin Robe, Yuri Kanno, Mitsunori Seo, Christian Dubos   +7 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Utility of local capillary supply indices: Insights from computational image‐based modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Local capillary distribution and fibre geometry influence oxygen availability in skeletal muscle. Image‐based modelling of tissue PO2${{P}_{{{{\mathrm{O}}}_2}}}$ shows that area‐based measures of capillary supply – the local capillary density (LCDi) and local maximum diffusion distance (Dmax,i) – most accurately represent the ...
Abdullah A. Al‐Shammari, Roger W. P. Kissane, Ali Ashkanani, Ashraf Al Madhoun, Fahd Al‐Mulla, Eamonn A. Gaffney, Stuart Egginton   +6 more
wiley   +1 more source

31P‐MRS of the Human Heart at 7 T With an Integrated Whole‐Body 31P Radiofrequency Transmit Coil

NMR in Biomedicine, Volume 39, Issue 4, April 2026.
We demonstrate the use of an integrated whole‐body phosphorus‐31 (31P) radiofrequency transmit coil for 31P‐MR spectroscopic imaging of the human heart at 7 T. Intersession measurement repeatability of the mid‐septal myocardial phosphocreatine (PCr) over adenosine triphosphate (ATP) concentration ratio in normal volunteers was 17.7%.
Mark W. J. M. Gosselink, Martijn Froeling, Kathy Verkerk, Dennis W. J. Klomp, Adrianus J. Bakermans, Jeanine J. Prompers   +5 more
wiley   +1 more source

Accelerating Conjugate Gradient Solvers for Homogenization Problems With Unitary Neural Operators

International Journal for Numerical Methods in Engineering, Volume 127, Issue 5, 15 March 2026.
ABSTRACT Rapid and reliable solvers for parametric partial differential equations (PDEs) are needed in many scientific and engineering disciplines. For example, there is a growing demand for composites and architected materials with heterogeneous microstructures.
Julius Herb, Felix Fritzen
wiley   +1 more source

Breaking Barriers in High‐Order Spectral Methods: The Intrinsic Matrix Approach

International Journal for Numerical Methods in Engineering, Volume 127, Issue 5, 15 March 2026.
ABSTRACT This paper introduces a unified framework in Hilbert spaces for applying high‐order differential operators in bounded domains using Chebyshev, Legendre, and Fourier spectral methods. By exploiting the banded structure of differentiation matrices and embedding boundary conditions directly into the operator through a scaling law relating ...
Osvaldo Guimarães, José R. C. Piqueira
wiley   +1 more source

Ghost effect from Boltzmann theory

Communications on Pure and Applied Mathematics, Volume 79, Issue 3, Page 558-675, March 2026.
Abstract Taking place naturally in a gas subject to a given wall temperature distribution, the “ghost effect” exhibits a rare kinetic effect beyond the prediction of classical fluid theory and Fourier law in such a classical problem in physics. As the Knudsen number ε$\varepsilon$ goes to zero, the finite variation of temperature in the bulk is ...
Raffaele Esposito, Yan Guo, Rossana Marra, Lei Wu   +3 more
wiley   +1 more source

Statistical and Numerical Analysis of Conjugate Heat and Momentum Transfer in an Open Cavity With a Thick Wall Using Cu–Water Nanofluid

Engineering Reports, Volume 8, Issue 3, March 2026.
Considered physical model and effect of Nuav(τ = 0.1) for Re and ϕ at τ = 0.1. ABSTRACT Although open cavity configurations are common in modern electronic and solar applications, limited attention has been given to thick‐walled hollow cavity designs, particularly in the context of comprehensive sensitivity analysis.
Murad Hossen, Abul Kalam Azad, Raita Rahman, Maisha Nusrat, Tahiya Hossain, Md Mustafizur Rahman   +5 more
wiley   +1 more source