Results 71 to 80 of about 25,372 (159)

Dental Biofilm–Induced Gingivitis in Children and Adolescents Without Known Systemic Involvement: A Systematic Review

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To synthesize evidence on gingival diseases and conditions in children and adolescents (< 18 years) without known systemic disorder involvement, focusing on their distribution, aetiology, diagnosis, management and oral health–related quality of life (OHRQoL).
Georgios Tsilingaridis   +4 more
wiley   +1 more source

Enhancing CRISPR‐Cas12a base editing in plants with LbCas12a variants and introns

open access: yesJournal of Integrative Plant Biology, EarlyView.
Intron optimization of LbCas12a‐RRV improves cytosine and adenine base editing efficiency in plants, supports multiplexed and double‐strand break‐free genome modification, and expands precise genome engineering tools for crop breeding and plant functional research. ABSTRACT Cytosine base editors (CBEs) and adenine base editors (ABEs) are powerful tools
Yanhao Cheng   +5 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Utility of local capillary supply indices: Insights from computational image‐based modelling

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Local capillary distribution and fibre geometry influence oxygen availability in skeletal muscle. Image‐based modelling of tissue PO2${{P}_{{{{\mathrm{O}}}_2}}}$ shows that area‐based measures of capillary supply – the local capillary density (LCDi) and local maximum diffusion distance (Dmax,i) – most accurately represent the ...
Abdullah A. Al‐Shammari   +6 more
wiley   +1 more source

Monitoring and control of a continuous, integrated filtration‐drying system with in‐line mass spectrometry via PharmaPy

open access: yesAIChE Journal, Volume 72, Issue 6, June 2026.
Abstract This article demonstrates the integration of in‐line mass spectrometry as a process analytical technology (PAT) tool with model‐based soft sensors in a continuous filtration‐drying carousel system for solid–liquid separation (SLS) of crystal slurries.
Inyoung Hur   +3 more
wiley   +1 more source

Pancreatic Islet Cell Crosstalk: Insight Into α‐/β‐Cell Compensatory Mechanisms

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
α‐cell remodeling compensates for impaired β‐cell function. Intra‐islet glucagon/GLP‐1 signaling is upregulated and becomes essential in prediabetic islets. Flexible receptor engagement reflects functional plasticity in hormonal control of insulin secretion. Created in BioRender. Plecita, L. (2026); https://BioRender.com/pgjjg3m.
Štěpánka Benáková   +5 more
wiley   +1 more source

A Novel Mixed‐Hybrid, Higher‐Order Accurate Formulation for Kirchhoff–Love Shells

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 2, June 2026.
ABSTRACT This paper presents a novel mixed‐hybrid finite element formulation for Kirchhoff–Love shells, designed to enable the use of standard C0$C^0$‐continuous higher‐order Lagrange elements. This is possible by introducing the components of the moment tensor as a primary unknown alongside the displacement vector, circumventing the need for C1$C^1 ...
Jonas Neumeyer, Thomas‐Peter Fries
wiley   +1 more source

A Compact Algorithm for Applying Periodic Boundary Conditions in 3D RVE Modeling with Abaqus

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 2, June 2026.
ABSTRACT Periodic boundary conditions (PBCs) are essential in multiscale modeling for computing the effective properties of heterogeneous materials via representative volume elements (RVEs). While several automated solutions have been developed for implementing PBCs in finite element software, many rely on structured node classification and predefined ...
Reza Sadeghpour, Martin Kraska
wiley   +1 more source

On Cahn–Hilliard Type Viscoelastoplastic Two‐Phase Flows

open access: yesProceedings in Applied Mathematics and Mechanics, Volume 26, Issue 2, June 2026.
ABSTRACT This contribution deals with a model for viscoelastoplastic two‐phase flows of Cahn–Hilliard type. We present the modeling framework for the flow, the notion of a generalized solution, namely the so‐called dissipative solution, and the key ideas of the existence proof.
Fan Cheng   +2 more
wiley   +1 more source

Advances in Erectile Dysfunction Management: What Does Work

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Erectile dysfunction (ED) is a prevalent and multifactorial disorder that substantially affects quality of life. Pathophysiology includes vascular, neurogenic, drug‐induced, and psychogenic causes, and frequently coexists with cardiometabolic disease.
Jolie Shen   +3 more
wiley   +1 more source

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