Results 81 to 90 of about 166,339,283 (190)
Abstract Hyperpolarization‐activated, cyclic nucleotide‐gated (HCN) channels are important regulators of cardiac pacemaking and neuronal excitability, yet their temperature dependence has not been compared systematically across mammalian isoforms and species in standardized experimental conditions. Here, we performed a standardized electrophysiological
Rajnish Ranjan +5 more
wiley +1 more source
”New Connections between dynamical systems and Hamiltonian PDEs”
This is a course of 8 hours on Hamiltonian PDEs: main examples, Nash-Moser IFT, tame estimates of the inverse linearzied operator, application to NLS and ...
BERTI, MASSIMILIANO
core
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti +2 more
wiley +1 more source
Utility of local capillary supply indices: Insights from computational image‐based modelling
Abstract figure legend Local capillary distribution and fibre geometry influence oxygen availability in skeletal muscle. Image‐based modelling of tissue PO2${{P}_{{{{\mathrm{O}}}_2}}}$ shows that area‐based measures of capillary supply – the local capillary density (LCDi) and local maximum diffusion distance (Dmax,i) – most accurately represent the ...
Abdullah A. Al‐Shammari +6 more
wiley +1 more source
Subspace Acceleration for Efficient Nonlinear Water Wave Simulation
We introduce an exponentially weighted subspace acceleration technique to reduce GMRES iterations for solving the Poisson equation with time‐dependent coefficients in nonlinear, dispersive free‐surface flows governed by the incompressible Navier‐Stokes equations. The method significantly reduces memory requirements and computational complexity compared
Rasmus Kleist Hørlyck Sørensen +3 more
wiley +1 more source
Indirect RBFN method with scattered points for numerical solution of PDEs [PDF]
This paper is concerned with the use of the indirect radial basis function network (RBFN) method in solving partial differential equations (PDEs) with scattered points.
Mai-Duy, Nam
core +1 more source
Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley +1 more source
ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes
ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi +8 more
wiley +1 more source
Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman +3 more
wiley +1 more source
Random Carbon Tax Policy and Investment Into Emission Abatement Technologies
ABSTRACT We analyze the problem of a profit‐maximizing electricity producer, subject to carbon taxes, who decides on investments into CO2$\rm CO_2$ abatement technologies. We assume that the carbon tax policy is random and that the investment in the abatement technology is divisible, irreversible, and subject to transaction costs.
Katia Colaneri +2 more
wiley +1 more source

