Results 31 to 40 of about 62,883 (260)
Clinical, Cosmetic and Investigational Dermatology, 2022 Ahmad Khalid Aalemi,1,2 Abdul Ghafar Hamdard,2 Ahmad Shekeb Sobat3 1Department of Oral Medicine, Kabul University of Medical Sciences, Kabul, 1001, Afghanistan; 2Department of Dermatology, Maiwand Teaching Hospital, Kabul University of Medical Sciences ...
Aalemi AK, Hamdard AG, Sobat AS
doaj
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
Advanced Functional Materials, EarlyView.A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery
Advanced Functional Materials, EarlyView.This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar +4 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Hierarchical coordination engineering redistributes Li+ from anion‐dominated pairing toward polymer‐mediated binding. Strong primary sites promote salt dissociation, while distributed secondary sites sustain dynamic hopping pathways. This coordination landscape couples ion flux with polysulfide conversion, suppresses transport‐conversion decoupling ...
Zhong‐Wei Zheng +8 more
wiley +1 more source
Molecules, 2023 Perylenediimide (PDI) compounds are widely used as the active units of thin-film organic lasers. Lately, PDIs bearing two sterically hindering diphenylphenoxy groups at the 1,7-bay positions have received attention because they provide a way to red-shift
Nathalie Zink-Lorre +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.The design of intrinsically robust stretchable semiconducting polymers was achieved through OTBS‐mediated post‐functionalization of PDPP2T side chains with UPy units, generating dual hydrogen‐bonding motifs comprising weaker urethane linkages and strong quadruple UPy interactions along the long alkyl side chain, which is crucial for achieving desirable
Dinda Bazliah +7 more
wiley +1 more source
Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy
Cancer Medicine, 2021 The protein disulphide isomerase (PDI) gene family is a large, diverse group of enzymes recognised for their roles in disulphide bond formation within the endoplasmic reticulum (ER).
Lauren E. Powell, Paul A. Foster
doaj +1 more source
Chemically Fueled Systems Chemistry Across Length Scales
Advanced Functional Materials, EarlyView.Chemically fueled reaction cycles regulate processes through single and multiple catalytic sites on the molecular and assembly scale. This gives rise to unique kinetically controlled properties/functions like spatio‐temporal catalysis, oscillations, optical properties, and perform work.
Brigitte A. K. Kriebisch, Job Boekhoven
wiley +1 more source
, 2022 Supplementary figure 1. Gut microbiota Alpha diversity of plant-based dietary scores (PDI): (a) PDI, (b) healthy PDI (hPDI), (c) unhealthy PDI (uPDI)
openaire +1 more source
Chinese Journal of Magnetic Resonance, 2022 Abnormally misfolded and aggregated α-synuclein (αsyn) is the hallmark of Parkinson's disease (PD). Molecular chaperone protein disulfide isomerase (PDI) has been shown to interact with αsyn and inhibit its aggregation in vitro, but the mechanism for the
PEI Yun-shan1,2, ZHANG Cai1,2, LIU Xiao-li1, CHENG Kai1, ZHANG Ze-ting,1, LI Cong-gang1
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