Results 41 to 50 of about 190,595 (336)
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
LA LIBERTAD RELIGIOSA EN ESPAÑA Y LA IRRUPCIÓN DE NUEVOS MOVIMIENTOS SOCIALES RELIGIOSOS
En este trabajo realizamos una breve exposición de las cuestiones históricas, políticas y legales que han influido en el desenvolvimiento de nuevos movimientos sociales religiosos en nuestro país.
Rocío de Diego Cordero
doaj +2 more sources
Ahmad Khalid Aalemi,1,2 Abdul Ghafar Hamdard,2 Ahmad Shekeb Sobat3 1Department of Oral Medicine, Kabul University of Medical Sciences, Kabul, 1001, Afghanistan; 2Department of Dermatology, Maiwand Teaching Hospital, Kabul University of Medical Sciences ...
Aalemi AK, Hamdard AG, Sobat AS
doaj
Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy
The protein disulphide isomerase (PDI) gene family is a large, diverse group of enzymes recognised for their roles in disulphide bond formation within the endoplasmic reticulum (ER).
Lauren E. Powell, Paul A. Foster
doaj +1 more source
Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44. [PDF]
Sulfatase modifying factor 1 (SUMF1) encodes for the formylglicine generating enzyme, which activates sulfatases by modifying a key cysteine residue within their catalytic domains. SUMF1 is mutated in patients affected by multiple sulfatase deficiency, a
Annunziata F. +10 more
core +1 more source
This study uncovers the unexplored role of intermolecular interactions in multiphoton absorption in coordination polymers. By analyzing [Zn2tpda(DMA)2(DMF)0.3], it shows how the electronic coupling of the chromophores and confinement in the MOF enhance two‐and three‐photon absorption.
Simon Nicolas Deger +11 more
wiley +1 more source
Perylenediimide (PDI) compounds are widely used as the active units of thin-film organic lasers. Lately, PDIs bearing two sterically hindering diphenylphenoxy groups at the 1,7-bay positions have received attention because they provide a way to red-shift
Nathalie Zink-Lorre +8 more
doaj +1 more source
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li +6 more
wiley +1 more source
Preparation, purification and characterization of aminopropyl-functionalized silica sol [PDF]
A new, simple and “green” method was developed for the surface modification of 20 nm diameter Stöber silica particles with 3-aminopropyl(diethoxy)methylsilane in ethanol. The bulk polycondensation of the reagent was inhibited and the stability of the sol
Attila Bóta +47 more
core +1 more source
Speckle‐Engineered Upconversion Amplification in Nanoemulsion‐Templated Hydrogel Microdomes
Nanoemulsion‐confined PEGDA microdomes generate speckle‐like excitation fields that strongly amplify upconversion luminescence upon dehydration, enabling filter‐free visible readout with reversible on–off switching. DMD‐based lithography yields scalable, shape‐programmable arrays for moisture‐responsive displays and optical encryption.
Chaeyeong Ryu +13 more
wiley +1 more source

