Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley +1 more source
Comparing novel backward hydrological models for watershed-scale precipitation estimation: an evaluation of inverted PDM and Kirchner-hybrid structures. [PDF]
Dastjerdi PA, Nasseri M.
europepmc +1 more source
Photoactivable Surfactant Design for In Situ Stabilization of Hydrogel Bioelectronics
Photoactivable surfactant additive enables in situ stabilization of hydrogel bioelectronics. ABSTRACT Conductive polymer hydrogels offer unique advantages for soft, stretchable biointerfaces by combining tissue‐like mechanics with high ionic conductivity.
Seungyeon Lee +11 more
wiley +1 more source
Interventions to Prevent Post-Discharge Mortality among Children in Sub-Saharan Africa: A Systematic Review. [PDF]
Cole K +16 more
europepmc +1 more source
Multilayered Digital Microfluidic Chip for Cell‐Based Assays
A multilayered digital microfluidic (mDMF) chip architecture is introduced to improve throughput and robustness in cell‐based assays. By multilayering electrode components and dielectric layers on glass, this design significantly reduces actuation voltage, maintains reliability, and enables expansion of the operational area with minimum current leakage.
Mert Ozden +2 more
wiley +1 more source
Rare Case of Persistent Descending Mesocolon Identified on Cross-Sectional Imaging. [PDF]
Maloo A +4 more
europepmc +1 more source
Ultrathin MXene/EMF composite foams achieve a specific shielding efficiency of 749.6 dB.dB·cm3$\mathrm{dB}\cdot {\mathrm{cm}}^{3}$/g, while the silver‐enhanced MXene/Ag/EMF reaches 81.4 dB shielding effectiveness at just 1.0 mm thickness. Both composites exhibit rapid Joule heating, retain stability up to 250∘C$^\circ{\rm C}$, and withstand 1000 ...
Abdullah A. Mahmood +7 more
wiley +1 more source
TRPV1 and TRPA1 channels exhibit bifurcated sensing of singlet oxygen and hydrogen peroxide. [PDF]
Chen Y +7 more
europepmc +1 more source
Neutron Reflectometry and Compression of Graded Hydrogel Surfaces
Highly‐entangled and covalently‐crosslinked hydrogels with thin and thick surface gel layers are compressed in neutron reflectometry experiments. Surface gel layer thickness dictates the extent to which the polymer network at the surface of a hydrogel collapses, while crosslinking chemistry, and therefore elastic modulus, impacts the pressure at which ...
Kathryn E. Shaffer +12 more
wiley +1 more source

