Results 41 to 50 of about 42,791 (261)

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Dilemmas and Trade-Offs in Peacemaking: A Framework for Navigating Difficult Decisions

Politics and Governance, 2019
This article focuses on the dilemmas and trade-offs that third parties face when mediating violent political conflicts. Should they ignore human rights violations because pushing the issue could jeopardize relationships with political actors who grant ...
Anne Isabel Kraus, Owen Frazer, Lars Kirchhoff, Tatiana Kyselova, Simon J. A. Mason, Julia Palmiano Federer   +5 more
doaj   +1 more source

Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen, Li Gao, Xu Han, Yunyun Cao, Lanlan Zhang, Yi Wu, Xinrong Zhao, Wenjing Hu, Ruiyu Ma, Renyi Hua, Niu Li, Yanlin Wang, Jian Wang, Shuyuan Li   +13 more
wiley   +1 more source

Sitting in Many Camps—Innovative Approaches and Methods for First Nations‐Led Research Into Indigenous Peacebuilding

Australian Journal of Social Issues, EarlyView.
ABSTRACT In 2021, a desktop review was conducted of published references to First Nations peoples' approaches to conflict and its management in Australia (Project Stage One), culminating in a report published in 2024. This article focuses on Project Stage Two, a complex, innovative research undertaking building on the findings of Stage One, and being ...
Helen Bishop, Alysoun Boyle, Tania Sourdin, Bin Li   +3 more
wiley   +1 more source

‘Shelter is a Dignity’: Rental Racism, Stress and Housing (In)justice

Australian Journal of Social Issues, EarlyView.
ABSTRACT Australia's private rental sector is in crisis, and culturally and racially minoritised renters face compounded harms through both covert and everyday direct forms of rental racism. Drawing on five community‐based focus groups in Melbourne (n = 37), the paper explores how racism manifests across the rental pathway and how it structures the ...
Erika Martino, Ilan Wiesel, Ang Li, Rebecca Bentley   +3 more
wiley   +1 more source

Restorative Justice and Post-Genocide Reconciliation: Ethical Implications and Community Healing in Rwanda

Journal of Ethics in Higher Education
This paper explores the role of restorative justice in post-genocide reconciliation in Rwanda, focusing on its ethical implications and impact on community healing.
Jonas Musengimana
doaj   +1 more source

Cooling Holes in Polymer Spur Gears: A Critical Analysis of Heat Dissipation Benefits and Mesh Stiffness Penalties

Journal of Applied Polymer Science, EarlyView.
Cooling holes provide a simple passive cooling strategy for polymer spur gears, reducing maximum operating temperature by up to 9.39% while introducing a measurable gear mesh stiffness penalty. A validated response‐surface model reveals how hole size and location govern this thermal–mechanical trade‐off, enabling design optimization for thermally and ...
Abderrahim Baccar, Ahmed Samet, Ahmed Hammami, Nuno Dourado, Ali Akrout, Mohamed Haddar   +5 more
wiley   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Internal displacement and peace mediation [PDF]

Forced Migration Review, 2009
The need to protect the rights of persons displaced by conflict and find durable solutions to their displacement is inextricably linked to achieving a viable, sustainable peace.
Andrew Solomon
doaj  

Sinn Féin’s Tortuous Road to Power

Revue LISA, 2014
Sinn Féin, once an outcast of Northern Ireland political life, now sits in the power-sharing Executive alongside the Democratic Unionist Party. In order to secure such a position, it had to transform itself, abandoning deep-seated principles such as ...
Agnès Maillot
doaj   +1 more source