Results 121 to 130 of about 5,730,304 (286)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Use of Microtechnology to Quantify the Peak Match Demands of the Football Codes: A Systematic Review

open access: yesSports Medicine, 2018
BackgroundQuantifying the peak match demands within the football codes is useful for the appropriate prescription of external training load. Wearable microtechnology devices can be used to identify the peak match demands, although various methodologies ...
S. Whitehead   +3 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Detecting presence of cardiovascular disease through mitochondria respiration as depicted through biophotonic emission

open access: yesRedox Biology, 2016
Aims: Increased production of reactive oxygen species (ROS) in mitochondria, play an important role in the cardiovascular system. Furthermore, oxidative metabolism of mitochondria comprised of biophoton emissions, are linked to ROS and oxidative stress ...
Nancy R. Rizzo   +2 more
doaj   +1 more source

Induced Compton Scattering in Gigahertz Peak Spectrum Sources

open access: yes, 1997
We revisit the shocked shell model for the class of Active Galactic Nuclei known as Gigahertz Peak Spectrum sources, incorporating new observational data on the radiation brightness temperatures. We argue that in addition to free-free absorption, induced
Coppi P.   +6 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Growth of Chlorella spp. in Tauge Extract Medium (TEM) with Various Initial pH

open access: yesMakara Seri Sains, 2005
Research on the effect of tauge extract medium initial pH value on Chlorella Beijerinck cell densities at peak condition had been done. The research was an experimental study with complete random design with 5 treatments (tauge extract medium with ...
Berta Putri   +2 more
doaj  

Review and Analysis of Peak Tracking Techniques for Fiber Bragg Grating Sensors

open access: yesItalian National Conference on Sensors, 2017
Fiber Bragg Grating (FBG) sensors are among the most popular elements for fiber optic sensor networks used for the direct measurement of temperature and strain.
D. Tosi
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The strengthening of reentrant pinning by collective interactions in the peak effect

open access: yes, 2009
Since it was first observed about 40 years ago [1], the peak effect has been the subject of numerous research mainly impelled by the desire to determine its exact mechanisms.
Altounian, Z., Hilke, M., Lefebvre, J.
core   +1 more source

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