Results 71 to 80 of about 38,801 (295)

Economic Low‐Carbon Chemical Production via Paired Electrolysis of Carbon Monoxide (CO) and 5‐hydroxymethylfurfural (HMF)

Advanced Materials, EarlyView.
Replacing CO2 with CO at the cathode and integrating a catholyte‐layer membrane electrode assembly transforms paired electrolysis into a stable platform for co‐producing ethylene and 2,5‐furandicarboxylic acid. Combined experimental and techno‐economic analyses identify carbon monoxide and 5‐hydroxymethylfurfural as the most compatible pairing ...
Mi‐Young Lee, Dongjin Kim, Jun Woo Park, Geunsu Bae, Byeong Cheul Moon, Younghyun Chae, Chang Hyuck Choi, Woong Kim, Ung Lee, Da Hye Won, Dong Ki Lee   +10 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Optimal Scheduling of Electric Vehicles for Peak Load Regulation: A Multi-Time Scale Approach with Comprehensive Evaluation and Feedback

Energies
With the increasing prevalence of electric vehicles (EVs), optimizing their scheduling for grid peak-shaving has become a focal point of research. This study develops a multi-time-scale optimization model for EV clusters to participate in peak shaving ...
Fei Xue, Wei Xiong, Jiahao Chen, Yonghai Yi, Zehui Liu, Jun Zeng, Junfeng Liu   +6 more
doaj   +1 more source

Energy Storage Sharing Strategy in Distribution Networks Using Bi-level Optimization Approach

, 2017
In this paper, we address the energy storage management problem in distribution networks from the perspective of an independent energy storage manager (IESM) who aims to realize optimal energy storage sharing with multi-objective optimization, i.e ...
Chen, Huimiao, Hu, Zechun, Luo, Haocheng, Rajagopal, Ram, Tan, Chin-Woo, Yu, Yang   +5 more
core   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

A Three-Step Methodology to Improve Domestic Energy Efficiency [PDF]

, 2010
Increasing energy prices and the greenhouse effect lead to more awareness of energy efficiency of electricity supply. During the last years, a lot of technologies have been developed to improve this efficiency.
Bakker, Vincent, Bosman, Maurice G.C., Hurink, Johann L., Molderink, Albert, Smit, Gerard J.M.   +4 more
core   +5 more sources

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source