Results 21 to 30 of about 33,167 (263)

A study on development of new juice product comprising pears and melon

open access: yesJournal of Agriculture, Food and Environment, 2021
The study was carried out in order to achieve appropriate formulation for the development of chilled fruits juice by considering safety issues, regulation, technological aspect, costing and shelf-life investigation as well. A
M. S. K. Azad
doaj   +1 more source

Pear Trees

open access: yesBulletin of popular information - Arnold Arboretum, Harvard University., 1920
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +4 more sources

How do lifestyle factors modify the association between genetic predisposition and obesity-related phenotypes? A 4-way decomposition analysis using UK Biobank

open access: yesBMC Medicine
Background Obesity and central obesity are multifactorial conditions with genetic and non-genetic (lifestyle and environmental) contributions. There is incomplete understanding of whether lifestyle modifies the translation from respective genetic risks ...
Mengrong Zhang   +6 more
doaj   +1 more source

Analysis of Volatile Compounds and Sugar Content in Three Polish Regional Ciders with Pear Addition

open access: yesMolecules, 2020
Aroma plays important part in cider acceptability to the consumer. In this study, techniques such as headspace solid-phase microextraction (HS-SPME), which has been coupled with gas chromatography and mass spectrometry, have been used to assess what ...
Jarosław Kliks   +4 more
doaj   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang   +8 more
wiley   +1 more source

Incidence and outcomes of patients hospitalised with COPD in Greater Glasgow and Clyde, Scotland 2015–2022: a retrospective cohort study

open access: yesBMC Pulmonary Medicine
Background Chronic Obstructive Pulmonary Disease (COPD) significantly impacts patients' quality of life and healthcare systems, especially among socio-economically deprived populations.
Navpreet Kaur   +16 more
doaj   +1 more source

Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction

open access: yesCell Reports
Summary: The CTLA-4 and PD-1 checkpoints control immune responses and are key targets in immunotherapy. Both pathways are connected via a cis interaction between CD80 and PD-L1, the ligands for CTLA-4 and PD-1, respectively. This cis interaction prevents
Maximillian A. Robinson   +11 more
doaj   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

open access: yesAdvanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka   +3 more
wiley   +1 more source

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source

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