Results 21 to 30 of about 33,020 (264)
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +4 more sources
Background Obesity and central obesity are multifactorial conditions with genetic and non-genetic (lifestyle and environmental) contributions. There is incomplete understanding of whether lifestyle modifies the translation from respective genetic risks ...
Mengrong Zhang +6 more
doaj +1 more source
Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction
Summary: The CTLA-4 and PD-1 checkpoints control immune responses and are key targets in immunotherapy. Both pathways are connected via a cis interaction between CD80 and PD-L1, the ligands for CTLA-4 and PD-1, respectively. This cis interaction prevents
Maximillian A. Robinson +11 more
doaj +1 more source
Liquid Metal‐Based Stretchable Strain Sensor for Fruit Growth Monitoring
Schematic overview of the fruit growth sensor development workflow, including sensor fabrication by injection molding, electromechanical and environmental characterization, mechanical stability testing, electronic readout integration, and outdoor field validation for monitoring of fruit growth under practical orchard conditions.
Asad Ullah +7 more
wiley +1 more source
Analysis of Volatile Compounds and Sugar Content in Three Polish Regional Ciders with Pear Addition
Aroma plays important part in cider acceptability to the consumer. In this study, techniques such as headspace solid-phase microextraction (HS-SPME), which has been coupled with gas chromatography and mass spectrometry, have been used to assess what ...
Jarosław Kliks +4 more
doaj +1 more source
3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu +11 more
wiley +1 more source
Growing evidence suggests that visiting heritage, such as historic buildings, or landscapes, may enhance mental health. However, adults and children from deprived areas are less likely to visit heritage, perhaps partly due to unequal geographical ...
Laura Macdonald +2 more
doaj +1 more source
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Background Randomised controlled trials are often criticised for excluding people with multiple long-term conditions. This study used individual participant data for 25 trials of sodium glucose co-transporter-2 inhibitors (SGLT2i) to compare baseline ...
Peter Hanlon +15 more
doaj +1 more source

