Results 171 to 180 of about 2,167 (210)
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Effects of pectenotoxin‐1 on liver cells in vitro
Natural Toxins, 1994AbstractThe effects of pectenotoxin‐I (PTX1), a nondiarrheagenic toxin from mussels, on liver cells were investigated by fluorescence microscopy. The in vitro application of PTX1, to these cells induced reduction in number and loss in radial arrangement of microtubules.
Z H, Zhou +3 more
openaire +2 more sources
Studies of diarrhetic activity on pectenotoxin-6 in the mouse and rat
Toxicon, 2008Diarrhetic activity of pectenotoxin-6 (PTX6), a shellfish contaminant in Japanese scallops (Patinopecten yessoensis), was studied in vivo. Mice gavaged with 5mg/kg PTX6 did not show diarrhea or fluid secretion, and no prominent pathological changes were observed.
Toshiyuki Suzuki +2 more
exaly +3 more sources
Toxicon, 2004
We have developed a simple and effective method for isolating pectenotoxin-2 (PTX-2) from Dinophysis cells collected from a natural bloom. A two-step extraction procedure followed by two column chromatography steps produced PTX-2 in high purity suitable for use as an analytical standard and for toxicological studies.
C. Miles +13 more
semanticscholar +4 more sources
We have developed a simple and effective method for isolating pectenotoxin-2 (PTX-2) from Dinophysis cells collected from a natural bloom. A two-step extraction procedure followed by two column chromatography steps produced PTX-2 in high purity suitable for use as an analytical standard and for toxicological studies.
C. Miles +13 more
semanticscholar +4 more sources
Access to Both Anomers of Pectenotoxin Spiroketals by Kinetic Spiroketalization
Organic Letters, 2004[structure: see text] A concise synthesis of both AB ring spiroisomers of the pectenotoxins is described. The nonanomeric AB spiroketal ring system of the pectenotoxins-1, -2, -3, and -6 is formed under very mild, kinetic spiroketalization conditions, along with the anomeric isomer.
Petri M, Pihko, Jatta E, Aho
openaire +2 more sources
ChemInform Abstract: Total Synthesis of Pectenotoxin‐2.
ChemInform, 2014AbstractA cytotoxicity assay against HepG2 and Caco2 cancer cells is reported and the compound (I) shows potent activity.
Kenshu Fujiwara, et al. et al.
openaire +1 more source
ChemInform, 1998
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. DAIGUJI +6 more
openaire +1 more source
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. DAIGUJI +6 more
openaire +1 more source
Enzymatic hydrolysis of esterified diarrhetic shellfish poisoning toxins and pectenotoxins
Analytical and Bioanalytical Chemistry, 2007Okadaic acid (OA) and dinophysistoxins-1 and -2 (DTX1, DTX2), the toxins responsible for incidents of diarrhetic shellfish poisoning (DSP), can occur as complex mixtures of ester derivatives in both plankton and shellfish. Alkaline hydrolysis is usually employed to release parent OA/DTX toxins, and analyses are conducted before and after hydrolysis to ...
Doucet, Erin +2 more
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Synthesis of the common left-half part of pectenotoxins
Tetrahedron Letters, 2005Abstract The common left-half [C31–C33(OC1–C7)–C40] part of pectenotoxins has been synthesized convergently from the C31–C35, C36–C40, and C1–C7 parts. The C31–C35 part, prepared via a new route shorter than our previous route, was coupled with the C36–C40 part through reductive lithiation and addition reactions to give an adduct stereoselectively ...
Kenshu Fujiwara +10 more
openaire +1 more source