Results 61 to 70 of about 25,837 (278)

Effect of neon seeding on the pedestal structure and stability in the JET-ILW deuterium JET-ITER baseline scenario using both ideal and resistive MHD

Nuclear Fusion
In this work, the effect of neon seeding in the JET-ILW JET-ITER baseline scenario on pedestal structure, global stability and local stability is studied.
H. Nyström, C. Giroud, L. Frassinetti, S. Menmuir, E. Litherland-Smith, J.M. Fontdecaba, D. Kos, Z. Huang, A. Boboc, J. MacDonald, G. Szepesi, JET contributors, EUROfusion Tokamak Exploitation Team   +12 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Experimental and simulation studies on ELM characteristics under a plasma current ramping up discharge on EAST

AIP Advances
Previous experimental results show that the poloidal mode spacing of the filamentary structures increases and the dominant toroidal mode number decreases in the edgelocalized mode (ELM) rising phase with increasing plasma current.
Bang Li, Tingfeng Ming, Yanlong Li, Qiqi Shi, Rongjing Deng, Shanwei Hou, Xiaohe Wu, Yanjie Yang, Kaixuan Fan, Xiaoju Liu, Tianyang Xia, Qing Zang, Xiang Gao, GuoQiang Li   +13 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research on the Load Bearing and Impact Resistance of a Novel Structure Exhibiting Both Positive and Negative Poisson’s Ratios

Shock and Vibration
A ship equipment pedestal is a structure that connects power equipment to a hull. It must have a high load-bearing capacity and the ability to withstand large impact loads.
Xidong Zhang, Hongyu Cui, Haoming Hu, Xiaokai Yin, Huanqiu Xu   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Investigating pedestal dependencies at JET using an interpretable neural network architecture

Nuclear Fusion
We present NeuralBranch, an interpretable neural network framework. In this work, we use it specifically to predict the pedestal from key engineering parameters in tokamak fusion experiments.
A. Gillgren, A. Ludvig-Osipov, D. Yadykin, P. Strand, JET contributors   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source