Results 81 to 90 of about 25,837 (278)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Role of turbulent separatrix tangle in the improvement of the integrated pedestal and heat exhaust issue for stationary-operation tokamak fusion reactors

Nuclear Fusion
The magnetic separatrix surface is designed to provide the final and critical confinement to the hot stationary-operation core plasma in modern tokamak reactors in the absence of an external magnetic perturbation (MP) or transient magneto-hydrodynamic ...
C.S. Chang, S. Ku, R. Hager, J. Choi, D. Pugmire, S. Klasky, A. Loarte, R.A Pitts   +7 more
doaj   +1 more source

Plinths and Pedestals

The Mathematical Intelligencer
In this paper we explain what are the plinths and the pedestals of the skyscrapers (=plane partitions), and how one can use them in order to count the skyscrapers.
Ogievetsky, Oleg, Shlosman, Senya
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Golden oak pedestal table

, 2005
Support furnitureWalnut pedestal table with golden oak stained finish, round top with plain frieze, on plain turned pedestal with four shaped feet. Part of a five-piece set consisting of a table and four chairs. Signed.walnut2 1/2"h x 4"
Carlisle, Robert L.
core  

Non-ideal MHD analysis of pedestal scans of AUG and JET

Nuclear Fusion
The extended MHD code CASTOR3D is used to perform the MHD stability analysis of predictive pedestal scans of standard ASDEX Upgrade and JET-ILW scenarios.
F. Stefanelli, M.G. Dunne, J. Puchmayr, H. Zohm   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The physics of ballooning-limited ELM-free regimes in EUROfusion tokamaks

Nuclear Fusion
The development of operational scenarios without large Type-I ELMs is of utmost importance for the stable operation and longevity of future tokamaks. The EUROfusion tokamak exploitation program has therefore made the understanding of ELM-free regimes a ...
M.G. Dunne, M. Faitsch, O. Sauter, E. Viezzer, B. Labit, A. Kappatou, D. Keeling, B. Vanovac, I. Balboa, P. Bilkova, P. Bohm, D. Kos, J. Hobirk, E. Lerche, P. Lomas, S. Menmuir, T. Pütterich, L. Radovanovic, S. Saarelma, S. Silburn, D. Silvagni, E.R. Solano, H.J. Sun, A. Tookey, The ASDEX Upgrade Team, The TCV Team, The EUROfusion Tokamak Exploitation Team, JET Contributors   +27 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source