Results 101 to 110 of about 143,542 (285)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Progress in pedestal and edge physics: Chapter 3 of the special issue: on the path to tokamak burning plasma operation

Nuclear Fusion
This paper describes the extensive progress that has been made in the understanding of tokamak pedestal physics since the 2007 publication of ‘Progress in the ITER Physics Basis’ (Ikeda 2007 Nucl. Fusion 47 E01–S500).
M.E. Fenstermacher (Chair, Pedestal and Edge Physics), L.R. Baylor, E. de la Luna, M.G. Dunne, G.T.A. Huijsmans, A. Kirk, F.M. Laggner, T.H. Osborne, C. Paz-Soldan, S. Saarelma, P.B. Snyder, E. Viezzer, M. Becoulet, K.H. Burrell, A. Cathey, X. Chen, M. Hoelzl, J.W. Hughes, R. Maingi, A.O. Nelson, H. Urano, E. Wolfrum, X.Q. Xu, A. Diallo, L. Frassinetti, S. Futatani, L. Gil, R. Groebner, T. Happel, S.H. Kim, J. King, B. Labit, P.T. Lang, Y.Q. Liu, Z.X. Liu, R. Lunsford, G.Y. Park, U. Sheikh, W. Suttrop, B. Vanovac, R.S. Wilcox, A. Wingen, T. Zhang   +42 more
doaj   +1 more source

Controlling Tokamak Geometry with 3D Magnetic Perturbations

, 2014
It is shown that small externally applied magnetic perturbations can significantly alter important geometric properties of magnetic flux surfaces in tokamaks.
Bird, Thomas M, Hegna, Chris C
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Un pedestal de estatua con inscripción de Pajaritos (Huelva) [PDF]

, 2010
Un pedestal con la dedicación de un aedilis y IIvir, de la tribu Quirina, confirma el estatus jurídico privilegiado de Onoba Aestuaria y descarta la condición jurídica de colonia para Onoba.
Gimeno Pascual, Helena, Martín Rodríguez, Enrique C., Pérez Macías, Juan Aurelio   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Impact of shape and global β on ASDEX Upgrade pedestal structure

Nuclear Fusion
The stability and confinement of the pedestal, the outermost region of the confined plasma in a tokamak, are crucial for its efficient operation and performance.
L. Radovanovic, E. Wolfrum, M.G. Dunne, G.F. Harrer, F. Aumayr, the ASDEX Upgrade Team   +5 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

EDA H-mode in ASDEX Upgrade: scans of heating power, fueling, and plasma current

Nuclear Fusion
Electron cyclotron resonance heating (ECRH) staircase discharges in strongly shaped plasmas were performed at the full-tungsten ASDEX Upgrade tokamak to investigate the enhanced D _α (EDA) H-mode, a high-confinement regime without edge localized modes ...
L. Gil, T. Pütterich, C. Silva, D. Hachmeister, G.D. Conway, P. David, M. Faitsch, R. Fischer, T. Happel, A. Kallenbach, J. Santos, A. Silva, J. Stober, U. Stroth, E. Viezzer, E. Wolfrum, the ASDEX Upgrade Team, the EUROfusion Tokamak Exploitation Team   +17 more
doaj   +1 more source

Measurement of jet quenching with I_CP and I_AA,Pythia in Pb-Pb collisions at sqrt(s_NN) = 2.76 TeV with ALICE

, 2011
This paper discusses the measurement of I_CP and I_AA,Pythia with ALICE (A Large Ion Collider Experiment). An away-side suppression is found expected from in-medium energy loss.
Grosse-Oetringhaus, Jan Fiete
core