Results 231 to 240 of about 313,083 (294)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

POP-YOLOv8: an object detection framework for partially occluded pedestrians in nighttime traffic environments. [PDF]

Sci Rep
Liu H, Zhang Z, Feng B.
europepmc   +1 more source

Smart Bioinspired Material‐Based Actuators: Current Challenges and Prospects

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This work gathers, in a review style, an extensive and comprehensive literature overview on the development of autonomous actuators based on synthetic materials, bringing together valuable knowledge from several studies. Furthermore, the article identifies the fundamental principles of actuation mechanisms and defines key parameters to address the size
Alejandro Palacios, Léon Chiriatti, Simon Poppinga, Thomas Speck, Vincent Le Houérou   +4 more
wiley   +1 more source

Unraveling nonlinear impacts of seasonal climate and built environments on exercise walking in high-density cities via a modified machine learning approach. [PDF]

Int J Health Geogr
Lu B, Long T, Li B, Chen Y, Zhu L.
europepmc   +1 more source

Tree canopy cover and injurious pedestrian falls: a location-based case-control study. [PDF]

Am J Epidemiol
Burford KG, Lo AX, Quinn JW, Crowe RP, Just AC, Kondo MC, Beard JR, Rundle AG.   +7 more
europepmc   +1 more source

RedMan-GreenMan: Co-Designed Pedestrian Safety Game Prototype for Children With Autism. [PDF]

JMIR Serious Games
Stanton JC, Peel NL, Mills CJ, Breen PP.
europepmc   +1 more source

Research on UAV Autonomous Trajectory Planning Based on Prediction Information in Crowded Unknown Dynamic Environments. [PDF]

Sensors (Basel)
Tang J, Yang S, Chen S, Li Q, Yin Q, Zhou S.   +5 more
europepmc   +1 more source

Evaluating route preview as an alternative to turn-by-turn navigation in pedestrian mobility. [PDF]

PLoS One
Savino GL, de Bellis E, Kirkham R, Schöning J.   +3 more
europepmc   +1 more source