Results 41 to 50 of about 22,949 (167)

Reflexões acerca do Ensino de Pediatria no Século XXI: o Cenário Brasileiro

Revista Brasileira de Educação Médica
RESUMO Introdução O Relatório Flexner é considerado o ponto de partida para a discussão do ensino da medicina no século XX. Após amplas discussões, em 2001, o Ministério da Educação homologa as Diretrizes Curriculares Nacionais do Curso de Graduação em
Andréia de Santana Silva Moreira, Alexandra Prufer Queiroz Campos Araújo, Márcia Gonçalves Ribeiro, Rodrigo Siqueira-Batista   +3 more
doaj   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Clinician Perspectives of Oxygen Control in Children With Bronchopulmonary Dysplasia at Home: An International Survey of Clinicians From 44 Countries

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth and may lead to difficulties with oxygen control even at home. How oxygenation is managed outside the hospital and in high and low resourced settings is unclear. Aims To determine clinician perspectives for managing oxygenation after hospital discharge
Thy A. N. Pham, James X. Sotiropoulos, Abhijeet Rakshasbhuvankar, Vineet Bhandari, Georg M. Schmölzer, R. Kishore Kumar, Satoshi Kusuda, Huayan Zhang, Thu‐Tinh Nguyen, Ratchada Kitsommart, Han‐Suk Kim, Li Ma, Fan Yang, Azanna Ahmad Kamar, Setya Dewi Lusyati, Kee Thai Yeo, Juin Yee Kong, Lloyd Tooke, Dominic Fitzgerald, Kate Gonski, Janneke Dekker, Gina Lim, Victor Javier Lara‐Díaz, Ju Lee Oei   +23 more
wiley   +1 more source

Urinary Tract Infections in Children: Changing Trends in Etiology and Local Resistance Patterns over a Three-Year Period

Acta Médica Portuguesa
Introduction: Urinary tract infections are common in pediatrics. Knowledge of local resistance patterns is crucial to guide empirical antibiotic therapy. We aimed to review the pathogens implicated in urinary tract infections, local resistance patterns,
Patrícia Sousa, Lucinda Delgado, Susana Correia-de-Oliveira, Cecília Pereira, Ângela Dias, Ana Cláudia Tavares   +5 more
doaj   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Intake of oligoelements with cytarabine or etoposide alters dopamine levels and oxidative damage in rat brain

Scientific Reports
Research on the relationships between oligoelements (OE) and the development of cancer or its prevention is a field that is gaining increasing relevance. The aim was to evaluate OE and their interactions with oncology treatments (cytarabine or etoposide)
David Calderón Guzmán, Norma Osnaya Brizuela, Maribel Ortíz Herrera, Hugo Juárez Olguín, Armando Valenzuela Peraza, Norma Labra Ruíz, Gerardo Barragán Mejía   +6 more
doaj   +1 more source

Crescimento e puberdade na diabetes mellitus tipo 1 – experiência de uma unidade de endocrinologia pediátrica

Acta Médica Portuguesa, 2012
Introdução: a Diabetes Mellitus tipo 1 (DM1) é a doença crónica endócrino-metabólica mais frequente em idade pediátrica. Associa-se a complicações vasculares e neuropáticas, podendo afectar também o crescimento e desenvolvimento. Objectivo: relacionar
Catarina Timóteo, Susana Castanhinha, Carolina Constant, Brígida Robalo, Carla Pereira, Lurdes Sampaio   +5 more
doaj   +1 more source

Genomic profiling of Mexican patients with B‐cell precursor acute lymphoblastic leukemia reveals clinically significant somatic and potential germline variants

The Journal of Pathology: Clinical Research, Volume 12, Issue 5, September 2026.
Abstract B‐cell precursor acute lymphoblastic leukemia (preB‐ALL) is characterized by pathogenic variants currently used in precision oncology. However, the mutational landscape of Mexican children with preB‐ALL has not yet been thoroughly explored and defined in terms of the clinical significance.
Daniel Martínez Anaya, María del Rocío Juárez‐Velázquez, Ulises Juárez Figueroa, Michael Dean, Consuelo Salas Labadía, Marian Valladares Coyotecatl, Adriana Reyes León, Norma López Santiago, Luis Juárez Villegas, Marta Zapata Tarrés, Patricia Pérez‐Vera   +10 more
wiley   +1 more source

Quilotórax recorrente – uma história com 15 anos

Revista Portuguesa de Pneumologia, 2004
RESUMO: Os autores descrevem o caso de uma adolescente de 15 anos com internamentos sucessivos por quilotórax bilateral desde os primeiros meses de vida.
Micaela Guardiano, Ana Lobo, Teresa Nunes, Luísa Vaz   +3 more
doaj   +1 more source

Long‐Term Effects of Real‐Time Remotely Supervised High‐Intensity Interval Training in Adolescents With Obesity

Obesity Science &Practice, Volume 12, Issue 4, August 2026.
ABSTRACT Background High‐intensity Interval Training (HIIT) has emerged as an effective strategy in the management of adolescents with obesity, including delivery through real‐time remote models. What remains unclear is whether these clinical benefits are sustained once direct professional supervision is discontinued.
Fábio de Freitas, Mariana R. Zago, Maria Ângela Antônio, Maria Ângela Bellomo Brandão, António Videira‐Silva   +4 more
wiley   +1 more source