Results 101 to 110 of about 1,918,801 (347)

Reproducibility and intraindividual variation over days in buccal cell DNA methylation of two asthma genes, interferon γ (IFNγ) and inducible nitric oxide synthase (iNOS)

Clinical Epigenetics, 2012
The biological mechanisms responsible for the onset and exacerbation of asthma symptoms in children may involve the epigenetic regulation of inflammatory genes after environmental exposures.
Torrone DZ, Kuriakose JS, Moors K, Jiang H, Niedzwiecki MM, Perera FF, Miller RL   +6 more
doaj   +1 more source

Pediatrics [PDF]

Operative Neurosurgery, 2019
Joshua J, Chern, Robert J, Bollo, Lance S, Governale, Kyle G, Halvorson, Kristopher, Hooten, Abhaya V, Kulkarni, William, Lo, François, Mathieu, Oliver, Mrowczynski, Joseph, Piatt, Elias, Rizk, Eric, Thompson   +11 more
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Is camel milk protein suitable for infants? Understanding mothers’ knowledge, attitudes, and practices

Frontiers in Sustainable Food Systems
IntroductionCamel milk, with its resemblance to human milk and therapeutic properties, has potential as a substitute/complementary food for infants. To commercialize camel milk and its products specifically for infants, this research was imperative to ...
Morgambal Padayachee, Samir K. H. Safi, Monia Kittana, Hessa Salem Al Derei, Muneera Khajjah, Mozah Salem Obaid Khameis Aldhanhani, Hessa Mohammed Helal Alrashedi, Priti Mudgil, Sajid Maqsood, Amita Attlee   +9 more
doaj   +1 more source

Target Enrichment Metagenomics Reveals Human Pegivirus-1 in Pediatric Hematopoietic Stem Cell Transplantation Recipients [PDF]

, 2022
Natali Ludowyke, Worakorn Phumiphanjarphak, Nopporn Apiwattanakul, Suwimon Manopwisedjaroen, Samart Pakakasama, Insee Sensorn, Ekawat Pasomsub, Wasun Chantratita, Suradej Hongeng, Pakorn Aiewsakun, Arunee Thitithanyanont   +10 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Sleep fragmentation in critically ill children: a review of contributing factors in the pediatric intensive care unit and neurodevelopmental outcomes

Frontiers in Sleep
Sleep is a critical neurobiological process essential for brain maturation, emotional regulation, cognitive development, and overall organ system homeostasis.
Alana GaHyun Byeon, Shelly K. Weiss, Shelly K. Weiss, Elaine Gilfoyle, Elaine Gilfoyle, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon   +8 more
doaj   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Appendicitis in Children: Evaluation of the Pediatric Appendicitis Score in Younger and Older Children [PDF]

, 2014
Martin Salö, Gustav Friman, Pernilla Stenström, Bodil Ohlsson, Einar Arnbjörnsson   +4 more
openalex   +1 more source