Results 81 to 90 of about 1,277,806 (307)

Treatment Patterns for and Characteristics of Headache in Children and Adolescents Aged 6–17 Years in Japan: A Retrospective Cross-Sectional and Longitudinal Analysis of Health Insurance Claims Data

Life
Objective: To investigate the prescription patterns for patients aged 6–17 years with headaches in the REZULT database. Methods: We cross-sectionally investigated (Study 1) the pattern of prescription and the proportion of triptan overprescription (≥30 ...
Masahito Katsuki, Yasuhiko Matsumori, Taisuke Ichihara, Yuya Yamada, Shin Kawamura, Kenta Kashiwagi, Akihito Koh, Tetsuya Goto, Kazuma Kaneko, Naomichi Wada, Fuminori Yamagishi   +10 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Prescription of Panoramic Radiographs in Children: A Health Services Assessment of Current Guidelines

, 2017
Purpose: To (1) determine adherence to guidelines when prescribing panoramic radiographs (PR) for patients 18 y.o. and younger; and 2) compare PR prescriptions between general dentists (GPs) and pediatric dentists (PDs). Methods: A retrospective analysis
Maupomé, Gerardo, Tang, Qing, Eckert, George J., Vinson, LaQuia, Powers, Elizabeth, Yepes, Juan F., Downey, Tim   +6 more
core  

The Performance of the Pediatric Trauma Score in a Pediatric Emergency Department: A Prospective Study

, 2017
Introduction: The aim of this study was to assess the efficacy of the Pediatric Trauma Score (PTS) in predicting significant trauma in patients presenting with blunt trauma to a high-level pediatric emergency department.
Yüksel Bıcılıoğlu, Fulya Kamit Can, Serdar Sarıtaş, Gamze Gökalp, Murat Anıl, Ayşe Berna Anıl   +5 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Therapeutic approaches in common pediatric bleeding disorders

, 2020
Although both morbidity and mortality have been improved due to advancements in management possibility, bleeding disorders in pediatric population are one of the most threatening diseases that bring concerns to the patients and their families as the ...
Takai, Yasuko
core  

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection [PDF]

, 2003
Although the pathogenesis of human immunodeficiency virus (HIV) infection and the general virologic and immunologic principles underlying the use of antiretroviral therapy are similar for all HIV-infected persons, there are unique considerations needed ...
Health Resources and Services Administration, HRSA, National Institutes of Health, NIH, Antiretroviral Therapy and Medical Management of HIV-Infected Children, ATMMHC, National Pediatric and Family HIV Resource Center, NPHRC   +3 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Nasal chondromesenchymal hamartoma, a rare pediatric tumor: Case report

The Turkish Journal of Pediatrics, 2016
Nasal chondromesenchymal hamartoma has characteristic clinicopathological features and it is accepted as the upper airway analogue of mesenchymal hamartoma of the chest wall.
Adnan Ünal, Rauf Oğuzhan Kum, Yonca Avcı, Devrim Tuba Ünal   +3 more
doaj   +1 more source

Embracing change : the era for pediatric ERAS is here

, 2019
The concept of Enhanced Recovery After Surgery (ERAS) has increasingly been embraced by our adult surgical colleagues, but has been slow to crossover to pediatric surgical subspecialties.
Herndon, C. Anthony,, Koyle, MA, Heiss, K, Scott, Michael J.,, Brindle, ME, Brindle, Mary E.,, Scott, MJ, Heiss, Kurt,, Ljungqvist, O,, Pediatric ERAS, (Enhanced Recovery After Surgery) Society), Koyle, Martin A.,, Herndon, CA, on, behalf Pediatric ERAS (Enhanced Recovery After Surgery) Society, Ljungqvist, Olle,   +13 more
core   +1 more source