Results 101 to 110 of about 1,277,806 (307)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Natural excretion of a metallic susceptor originating from an ingested heated tobacco stick

Clinical Case Reports
Key Clinical Message Clinicians should not only consider the presence of metallic foreign bodies within the digestive tract but also contemplate the possibility of nicotine poisoning during the diagnostic process. Abstract When clinicians encounter cases
Hirohito Doi, Toshihiko Kakiuchi, Masafumi Nishino, Masato Yoshiura   +3 more
doaj   +1 more source

Pediatric Patients with Osteomyelitis and/or Septic Joint Undergoing Surgical Debridement Have Equivalent Short-Term Outcomes with or without Preoperative MRI

Children
The purpose of this study was to determine if short-term outcomes differed for pediatric patients with suspected musculoskeletal infection with or without a preoperative MRI.
E. Graham Englert, Collin L. Braithwaite, Maria E. Aguirre-Flores, Aaron W. Lam, Mohamed Sarraj, Abigail Kumagai, E. Dimitra Bednar, Adam M. Gordon, Ibrahim Salama, Jacob Keeley, Indu Pathak, Waleed Kishta, Ahmed M. Thabet, Amr Abdelgawad, Ehab Saleh   +14 more
doaj   +1 more source

A significant number of pediatric inflammatory bowel disease patients are exposed to a medication not approved by the Food and Drug Administration for pediatric use

Objectives: Inflammatory bowel disease (IBD) presents before age 20 years in ~25% of patients. Regulatory approvals of IBD medications for pediatric use are often delayed.
Rusch, Courtney, Perkins, Anthony J., ImproveCareNow Pediatric IBD Learning Health System, Steiner, Steven J.   +3 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Wheelchair Dance: Exploring a Novel Approach to Enhance Wheelchair Skills, Belongingness and Inclusion among Children with Mobility Limitations

Disabilities
Playful approaches are recommended to enhance wheelchair skills training with young people. Inclusive dance allows participants to discover motor skills and improve social participation.
Jade Berthiaume, Claire Cherriere, Béatrice Ouellet, Laurence Éthier, Paula W. Rushton, Martin Lemay, Krista L. Best   +6 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Abstracts of the 2nd International Congress of Contemporary Pediatric Dentistry (ICCPD 2022)

Contemporary Pediatric Dentistry, 2022
Contemporary Pediatric Dentistry
doaj   +1 more source

Dental Radiography in Pediatric Dentistry

, 2019
Radiography is a very useful diagnostic tool in the oral examination of pediatric patients. Radiographic imaging techniques are a valuable tool in oral care for infants, children, adolescents and people with special care needs.
Heer, Nikkita
core  

Hot Topics in Safety for Pediatric Anesthesia

, 2020
Anesthesiology is one of the leading medical specialties in patient safety. Pediatric anesthesiology is inherently higher risk than adult anesthesia due to differences in the physiology in children.
Christy Crockett, Hannah Lovejoy, Amanda Lorinc, Srijaya Reddy, Camila Walters   +4 more
core   +1 more source