Results 201 to 210 of about 2,772,382 (389)
The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis
Advanced Science, EarlyView.Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.Jian Zhang, Yuee Zhao, Gauthami Pulivendala, Qing Zhang, Liangyou Rui, Jiashi Gao, Huiwen Wang, Gary Zhang, Alli Nuotio‐Antar, Xin Tong, Lei Yin +10 morewiley +1 more sourceSubungual exostosis of the thumb - first case report in youngest age
Indian Journal of Dermatology, 2009 Subungual exostosis (SE) is a benign osteocartilaginous tumor of the ungual apparatus, particularly of the toes. It affects both sexes equally, more frequently in the second and third decades of life. The present case highlights this entity (SE) in a six Gupta Sanjeev, Mittal Amit, Gupta Sunita, Mahendra Aneet, Dhull Anil +4 moredoaj Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model
Advanced Science, EarlyView.A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.Marco Andreana, Ryan Sentosa, Caterina Sturtzel, Martin Pfister, René Werkmeister, Anna Schmitt, David Traver, Rainer Leitgeb, Wolfgang Drexler, Martin Distel, Angelika Unterhuber +10 morewiley +1 more sourcePediatrics [PDF]
Operative Neurosurgery, 2019 Joshua J, Chern, Robert J, Bollo, Lance S, Governale, Kyle G, Halvorson, Kristopher, Hooten, Abhaya V, Kulkarni, William, Lo, François, Mathieu, Oliver, Mrowczynski, Joseph, Piatt, Elias, Rizk, Eric, Thompson +11 moreopenaire +2 more sourcesThe Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism
Advanced Science, EarlyView.The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, Martina Morini, Martina Ardito, Alessandra Eva, Vincenza Cerbone, Lucia Mauriello, Marianna Caterino, Margherita Ruoppolo, John M. Maris, Sharon J. Diskin, Achille Iolascon, Mario Capasso +20 morewiley +1 more sourceAmerican College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock
Critical Care Medicine, 2017 A. Davis, J. Carcillo, R. Aneja, A. Deymann, John C. Lin, Trung C. Nguyen, R. Okhuysen-Cawley, Monica S Relvas, R. Rozenfeld, P. Skippen, Bonnie J Stojadinovic, E. Williams, T. Yeh, F. Balamuth, J. Brierley, A. D. De Caen, I. Cheifetz, K. Choong, E. Conway, Timothy T. Cornell, A. Doctor, M. Dugas, J. Feldman, J. Fitzgerald, H. Flori, J. Fortenberry, A. L. Graciano, B. Greenwald, M. Hall, Y. Han, L. Hernan, J. Irazuzta, E. Iselin, É. W. van der Jagt, H. Jeffries, S. Kache, C. Katyal, N. Kissoon, A. Kon, Martha C. Kutko, G. MacLaren, T. Maul, R. Mehta, F. Odetola, Kristine A. Parbuoni, Raina M. Paul, M. Peters, S. Ranjit, K. Reuter-Rice, E. Schnitzler, Halden F. Scott, A. Torres, Jacki Weingarten-Abrams, S. Weiss, J. Zimmerman, A. Zuckerberg +55 moresemanticscholar +1 more source
