Results 41 to 50 of about 1,419,974 (261)

Prevalence of Abnormal Heart Weight After Sudden Death in People Younger than 40 Years of Age

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background After sudden cardiac death in people aged
Zachary J. Schoppen, Lauren C. Balmert, Steven White, Rachael Olson, Ponni Arunkumar, Lisa M. Dellefave‐Castillo, Megan J. Puckelwartz, Alfred L. George, Elizabeth M. McNally, Gregory Webster   +9 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Complex relationship between growth hormone and sleep in children: insights, discrepancies, and implications

Frontiers in Endocrinology
Growth hormone (GH) is crucial to growth and development. GH secretion is regulated by a complex feedback system involving the pituitary gland, hypothalamus, and other organs, and predominantly occurs during deep sleep.
Marco Zaffanello, Angelo Pietrobelli, Paolo Cavarzere, Alessandra Guzzo, Franco Antoniazzi   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Experience of pediatric to adult transition in immunology services: patient experience questionnaire and micro-costing analysis

Frontiers in Immunology
The effective transition from pediatric to adult care for individuals with chronic medical conditions should address the medical, psychosocial and educational needs of the cohort.
Catherine King, Katie Ridge, Katie Ridge, James Smyth, Aisling M. Flinn, Aisling M. Flinn, Timothy Ronan Leahy, Timothy Ronan Leahy, Niall Conlon, Niall Conlon   +9 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Construct validity of the pediatric Rome III criteria

, 2014
Functional gastrointestinal disorders (FGIDs) are common. The diagnosis of FGIDs is based on the Rome criteria, a symptom-based diagnostic classification established by expert consensus.
Pusatcioglu, Cenk K., Nichols-Vinueza, Diana X, Mintjens, Stijn, Velasco-Benítez, Carlos A., Nichols-Vinueza, Diana X., Pusatcioglu, Cenk K, Velasco-Benítez, Carlos A, Saps, Miguel   +7 more
core   +1 more source

Surgery in Pediatric Crohn's Disease: Indications, Timing and Post-Operative Management [PDF]

, 2017
Pediatric onset Crohn's disease (CD) tends to have complicated behavior (stricture or penetration) than elderly onset CD at diagnosis. Considering the longer duration of the disease in pediatric patients, the accumulative chance of surgical treatment is ...
김승
core   +1 more source