Results 161 to 170 of about 4,767,425 (261)

JUVENILE MYELOMONOCYTIC LEUKEMIA WITH TELOMERE SHORTENING: CASE REPORT

EJC Paediatric Oncology, 2023
Anita Frisanco Oliveira, Rafael Balceiro, Neysimelia Costa Villela, Luiz Fernando Lopes   +3 more
doaj   +1 more source

Implementation of a universal psychosocial screening program across the pediatric cancer treatment trajectory: a standard of care. [PDF]

Support Care Cancer
Barakat LP, Vargo S, Hammer SN, Reilly A, Phillips C, Burns-Lynch P, Schwartz LA, Perez MN.   +7 more
europepmc   +1 more source

Chromosomal Abnormalities, Drug Sensitivity and Resistance in Hematological Malignancies: A Comprehensive Overview by the Francophone Group of Hematological Cytogenetics (GFCH)

American Journal of Hematology, EarlyView.
ABSTRACT Chromosomal abnormalities have a major clinical impact on hematological malignancies, particularly with regard to treatment strategies. To preserve and consolidate fundamental knowledge in this rapidly evolving field, the Francophone Group of Hematological Cytogenetics (Groupe Francophone de Cytogénétique Hématologique, GFCH) conducted a ...
Florence Nguyen‐Khac, Audrey Bidet, Elise Chapiro, Nathalie Douet‐Guilbert, Jean‐Baptiste Gaillard, Nada Assaf, Nathalie Auger, Hend Chaker, Jasmine Chauzeix, Inge Govaerts, Hippolyte Guérineau, Christine Lefebvre, Pauline Roynard, Hélène Guermouche, Lucienne Michaux, Marie‐Bérengère Troadec, Lauren Véronèse   +16 more
wiley   +1 more source

Genetic Susceptibility to Anthracycline-Induced Cardiotoxicity in Australian Pediatric Cancer Patients: A Case-Control Study. [PDF]

JACC Adv
Halman A, Netylko J, Stolper J, Rossello FJ, Ludlow L, Mateos MK, Celermajer DS, Kumar S, Elliott DA, Conyers R.   +9 more
europepmc   +1 more source

A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation

American Journal of Hematology, EarlyView.
ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard, Tianjian Lin, Nana A. Peterson, Rebekah C. Gullberg, Yann Le Guen, Jasmine Moshiri, John G. Doench, Elizabeth S. Egan   +7 more
wiley   +1 more source

Territorial Socioeconomic Vulnerability and Clinical Outcomes in Pediatric Cancer at a Colombian Referral Center. [PDF]

Children (Basel)
Galeano-Páez C, Peñata-Taborda A, Brango H, Londoño-García P, Ospina-Martínez J, Polo J, Jaramillo-Bedoya G, Espitia-Pérez L.   +7 more
europepmc   +1 more source

Distinct Consequences of BCOR and BCORL1 Mutations in Myeloid Neoplasms and Bone Marrow Failure

American Journal of Hematology, EarlyView.
ABSTRACT BCOR and BCORL1 (BCOR/L1) mutations are observed in both myeloid neoplasms (MN) and bone marrow failure syndromes (BMF), but their clinical significance may differ. We analyzed 11 340 patients and identified 418 BCOR/L1‐mutated patients, focusing on differences between MN and BMF. Compared with MN, BMF was associated with younger age, a higher
Atsushi Marumo, Arda Durmaz, Christopher Haddad, Aashray Mandala, Felipe de Almeida Sartori, Akram Abushamma, Serhan Unlu, Xiaorong Gu, Zachary Brady, Matteo D'Addona, Kartik Lakhotiya, Luca Guarnera, Masanori Yoshida, Monika M. Toma, Mark D. Orland, Carlos Bravo‐Perez, Carmelo Gurnari, Koichi Takahashi, Tomasz Skorski, Stephan Hutter, Torsten Haferlach, Marcin Wlodarski, Valeria Visconte, Jaroslaw P. Maciejewski   +23 more
wiley   +1 more source

The landscape of structural variation in pediatric cancer. [PDF]

Cancer Cell
Greenhalgh R, Brady SW, Yang W, Flasch DA, Edmonson MN, Terekhanova NV, Liu Y, Wang J, Szlachta KA, Tian L, Putnam DK, Rahbarinia D, Kolekar P, Zhou X, Gerhard DS, Ma X, Zhang J.   +16 more
europepmc   +1 more source

Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen, Ulrik Kristoffer Stoltze, Pernille Axél Gregersen, Marianne Hoffmann, Morten Lyng Høgild, Mette Klarskov Andersen, Lise Barlebo Ahlborn, Lisa Lyngsie Hjalgrim, Karin A. W. Wadt   +8 more
wiley   +1 more source

FANCONI ANEMIA AND T-LYMPHOBLASTIC LYMPHOMA. REPORT OF TWO CASES

EJC Paediatric Oncology
María Muñoz Martínez, Anna Ruiz Llobet, María Trabazo del Castillo, Verónica Celis Passini, Nuria Conde Cuevas, Julián Sevilla Navarro, Albert Català Temprano   +6 more
doaj   +1 more source