Results 191 to 200 of about 4,767,425 (261)

Expert Strategies: Controversies in Management of Sinonasal Malignancies—Global Perspectives Through a Mixed Methods Approach

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNMs) are a rare group of diseases with limited high‐level evidence to guide management. Where data are currently lacking, contemporary management principles may be guided by clinical expertise and experience.
Garret Choby   +56 more
wiley   +1 more source

dsRADAR: Imaging and Detecting Cellular dsRNA by Repurposing RNA‐Binding Proteins

open access: yesAngewandte Chemie, EarlyView.
Double‐stranded RNA (dsRNA) plays an important role in the innate immune system, but can be misregulated in disease, leading to inflammation. Despite the importance of this motif, methods for detecting dsRNA remain limited. This work shows that ADAR3 can be repurposed to provide improved detection of dsRNA, which is demonstrated in the context of viral
Weina Cheng   +7 more
wiley   +2 more sources

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

open access: yesAnnals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca   +24 more
wiley   +1 more source

Health-related quality of life in young pediatric cancer survivors: The role of sarcopenia. [PDF]

open access: yesSupport Care Cancer
Marmol-Perez A   +10 more
europepmc   +1 more source

Pediatric Cancer Survivorship: A Review. [PDF]

open access: yesPediatr Ann
Foerst E   +4 more
europepmc   +1 more source

Activity of Direct KRAS(G12C) Inhibitors in Preclinical Models of Pediatric Cancer. [PDF]

open access: yesMol Cancer Ther
Price HE   +21 more
europepmc   +1 more source

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