Results 91 to 100 of about 848,680 (351)

Efficacy and Safety of Pediatric Critical Care Physician Telemedicine Involvement in Rapid Response Team and Code Response in a Satellite Facility [PDF]

, 2019
OBJECTIVES: Satellite inpatient facilities of larger children's hospitals often do not have on-site intensivist support. In-house rapid response teams and code teams may be difficult to operationalize in such facilities.
Berrens, Zachary J., Brady, Patrick W., Gosdin, Craig H., Tegtmeyer, Ken   +3 more
core   +2 more sources

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]

, 2009
PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra, Curley, Martha AQ, Flori, Heidi, Matthay, Michael A, Sapru, Anil   +4 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The Challenges and Strategies to Improve Family-centered Round: a Literature Review [PDF]

, 2012
The importance of family-centered care and the role of families in decision making are becoming more recognized today. Several studies have supported the implementation of family-centered care and its role in enhancing quality of care.
Utami, R. S. (Reni)
core  

Severe Mycoplasma Pneumoniae Infection in Children Admitted to Pediatric Intensive Care

The Pediatric Infectious Disease Journal, 2018
Mycoplasma pneumoniae is a common cause of community-acquired pneumonia and may cause life-threatening disease in children. We identified 30 (0.3%) confirmed M.
K. Moynihan, A. Barlow, C. Nourse, C. Heney, S. Schlebusch, L. Schlapbach   +5 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Sevoflurane improves respiratory mechanics and gas exchange in a case series of infants with severe bronchiolitis‐induced acute respiratory distress syndrome

Clinical Case Reports, 2018
Key Clinical Message This report describes the successful use of a new intervention to improve respiratory mechanics and gas exchange in a relatively homogeneous group of infants with severe bronchiolitis‐induced PARDS after failure of conventional ...
Mirco Nacoti, Jacopo Colombo, Oliviero Fochi, Daniele Bonacina, Francesco Fazzi, Giacomo Bellani, Ezio Bonanomi   +6 more
doaj   +1 more source

The implausibility of ‘usual care’ in an open system: sedation and weaning practices in Paediatric Intensive Care Units (PICUs) in the United Kingdom (UK) [PDF]

, 2015
Background: The power of the randomised controlled trial depends upon its capacity to operate in a closed system whereby the intervention is the only causal force acting upon the experimental group and absent in the control group, permitting a valid ...
B Ambuel, B Blackwood, B Blackwood, B Blackwood, B Blackwood, Bronagh Blackwood, C Maloney, CJL Newth, D Bieri, D Macrae, DL Jackson, E Ista, E Ista, F Frutos-Vivar, FK Foronda, FW Moler, J Rycroft-Malone, J Rycroft-Malone, J Rycroft-Malone, JA Durlak, K Harron, L Kohn, L Rose, LS Franck, Lyvonne Tume, M Cunliffe, NJ Vet, P O’Halloran, PA Jouvet, RP Dellinger, S Chawla, S Playfor, SI Merkel, SW Krechel, YN Poh   +34 more
core   +1 more source

Pediatric palliative care in the intensive care unit and questions of quality: a review of the determinants and mechanisms of high-quality palliative care in the pediatric intensive care unit (PICU).

Translational Pediatrics, 2018
This article reviews the state and practice of pediatric palliative care (PC) within the pediatric intensive care unit (PICU) with specific consideration of quality issues. This includes defining PC and end of life (EOL) care. We will also describe PC as
S. R. Short, R. Thienprayoon
semanticscholar   +1 more source