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Stimulator of Interferon Genes (STING) Triggers Adipocyte Autophagy
Innate immune signaling in adipocytes affects systemic metabolism. Cytosolic nucleic acid sensing has been recently shown to stimulate thermogenic adipocyte differentiation and protect from obesity; however, DNA efflux from adipocyte mitochondria is a ...
Kornél Z. Varga +8 more
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Type 2 diabetes mellitus (T2DM) in adolescents is a more rapidly progressive disease, associated with earlier and higher rates of microvascular complications than in adults.
Megan O. Bensignor +2 more
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Aim. It is known that children and adolescents with obesity are more prone to obstructive sleep apnea syndrome (OSAS) and that their lung function may show some disturbance.
Regula Corbelli +4 more
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Objectives: To examine the most recent literature and published science in determining any and all possible associations between pediatric obesity and pediatric urolithiasis.
Henry J. Paiste +4 more
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The impacts of exercise on pediatric obesity [PDF]
Over the last few decades, the rates of pediatric obesity have more than doubled regardless of sociodemographic categorization, and despite these rates plateauing in recent years there continues to be an increase in the severity of obesity in children ...
Ronald J. Headid III, Song-Young Park
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Non-invasive detection of early microvascular changes in juveniles with type 1 diabetes
Aims/Hypothesis The study aimed to assess the usefulness of capillaroscopy and photoplethysmography in the search for early vascular anomalies in children with type 1 diabetes.
Klaudia Bogusz-Górna +6 more
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Metabolically healthy overweight adolescents: definition and components [PDF]
Purpose In adolescents, the definition and clinical implications of metabolically healthy overweight (MHO) status have not been established. This study aimed to investigate the prevalence of MHO according to its most widespread definition, which is based
António Videira-Silva +2 more
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Cardiovascular Risks and Benefits of Medications Used for Weight Loss
Obesity is a complex disease influenced by many neurohormonal pathways which regulate body weight toward homeostasis. Presently, the disease of obesity effects over a billion individuals worldwide with scalable treatment options in dire need ...
Carolyn T. Bramante +8 more
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Monogenic diabetes – an unappreciated problem among physicians
Monogenic diabetes results from one or more mutations in a single gene. It is a relatively rare genetic condition, therefore, it was frequently unappreciated among clinicians.
Elżbieta Niechciał +4 more
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Growth hormone is meaningfully involved in the processes of tooth cells differentiation and tissue formation. The aim of the study was to evaluate the occurrence of dental anomalies: microdontia, macrodontia, hypodontia and developmental defects of ...
Natalia Torlińska-Walkowiak +4 more
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