Results 71 to 80 of about 682,435 (246)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Incidence and risk factors of cataract following pediatric pars plana vitrectomy

International Journal of Retina and Vitreous
Purpose To evaluate the incidence and risk factors for cataract following pediatric pars plana vitrectomy (PPV). Setting Tertiary referral center. Design Retrospective consecutive case series. Methods We included 242 eyes of 218 patients (
Antoine Bourgeois, Thibaut Chapron, Ismael Chehaibou, Florence Metge, Youssef Abdelmassih, Georges Caputo   +5 more
doaj   +1 more source

Neuro-Ophthalmological Manifestations in Children with Down Syndrome: Current Perspectives

Eye and Brain, 2021
Lavinia Postolache,1 Anne Monier,2 Sophie Lhoir1 1Department of Pediatric Ophthalmology, Queen Fabiola University Children’s Hospital, Université Libre de Bruxelles, Brussels, Belgium; 2Department of Pediatric Neurology, Queen Fabiola University Children’
Postolache L, Monier A, Lhoir S
doaj  

Analysis of clinical investigation (device) initial submissions received by the Medicines and Healthcare products Regulatory Agency between January 2022 and December 2025

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse clinical investigation‐device initial submissions received by the MHRA between January 2022 and December 2025. Methods Data on submissions were extracted from the clinical investigations unit data bank; software as medical devices were not included. The predefined primary end‐point was submission type.
Andrea Manfrin, Mark Grumbridge, Daniel Hill, Crina Cacou, Graham Warren, James Pound, Jacob George, Alejandro F. Frangi   +7 more
wiley   +1 more source

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Michigan Ophthalmology Pathway Program: Five Years of Aiming to Increase Diversity in Ophthalmology

Introduction: Ophthalmology is one of the least diverse medical subspecialties. The Michigan Ophthalmology Pathway (MOP) Program was created at the University of Michigan Medical School in 2017 to promote diversity in ophthalmology through early exposure
Kay, Anna, Juratli, Lena, Griggs, Mikaelah Johnson, Reddy, Karthik, Yacim, Mana, Nguyen, Mickey, Miller, Keith D., Sugar, Alan, Issa, Rafik, Kaplan, Ariane   +9 more
core   +1 more source

Quantifying the Impact of Research on Matching into Ophthalmology Residency

, 2018
Purpose This article aims to quantify the impact of research on matching into various tiers of ophthalmology residency programs. Design In this study, 340 applicants who matriculated into ophthalmology residency programs in the United States from the ...
Patel, Varesh, Khouri, Albert, Bargoud, Albert, Henseler, Robert, Kass, William, Thangamathesvaran, Loka   +5 more
core   +1 more source

A Case of Pediatric Myopia Complicated by Vitreous Cyst: A Unique Ophthalmic Challenge

Case Reports in Ophthalmological Medicine
Vitreous cysts represent uncommon ophthalmological conditions. Most patients are asymptomatic, but a minority may experience symptoms such as floaters or blurred vision.
Abdulaziz J. Al Qattan, Abdulrahman Alasqah, Rafaa Babgi   +2 more
doaj   +1 more source

Correlation of polygenic risk score and clinical phenotype in patients with genetic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n 
Sophie von Brauchitsch, Nils Hartung, Robin A. Karge, Bobby Koeleman, Samuel F. Berkovic, Danielle M. Andrade, Francesca Bisulli, Antonio Gambardella, Renzo Guerrini, Ingrid E. Scheffer, Ingo Helbig, Wolfram S. Kunz, Holger Lerche, Hiltrud Muhle, Christian Boßelmann, Savvas S. Papacostas, Mark I. Rees, Sanjay M. Sisodiya, Pasquale Striano, Lynnette Sadleir, Yvonne Weber, Dennis Lal, Costin Leu, Philipp S. Reif, Stefan Wolking, Felix Rosenow, Karl Martin Klein, for the Epi25 Collaborative   +27 more
wiley   +1 more source

Advancing vision care in children – bridging science, policy, and practice

BMC Pediatrics
Pediatric vision health is a cornerstone of child development, learning, and social well-being. This editorial synthesizes current advances, challenges, and emerging frontiers in childhood vision care as reflected in this collection, emphasizing equity ...
Bharat Gurnani, Dipesh Patel
doaj   +1 more source