Results 121 to 130 of about 59,410 (289)

CytoBatchFlagR: A Comprehensive Framework to Objectively Assess High‐Parameter Cytometry Data for Batch Effects

open access: yesCytometry Part A, EarlyView.
ABSTRACT Rapid advancements in mass and flow cytometry technologies have allowed researchers to generate and analyze high‐dimensional single cell datasets, often utilizing upwards of 40 protein markers. Such high‐parameter cytometry is increasingly used in longitudinal immunological studies, but technical variations across experimental batch runs can ...
Shruti Eswar   +5 more
wiley   +1 more source

Practical consensus recommendations for polytherapy involving stiripentol in Dravet syndrome: A nominal group approach

open access: yesEpilepsia Open, EarlyView.
Abstract Objectives Dravet syndrome (DS) is a drug‐resistant developmental and epileptic encephalopathy, often requiring three or more antiseizure medications (ASMs). Consequently, the therapeutic landscape is highly complex, combining DS‐specific agents (stiripentol, STP; cannabidiol, CBD; fenfluramine, FFA), non‐specific ASMs, and non‐pharmacologic ...
J. Helen Cross   +4 more
wiley   +1 more source

Association of Childhood Acute Leukemia With Autoimmune Diseases

open access: yesInternational Journal of Cancer, EarlyView.
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka   +4 more
wiley   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

open access: yesJournal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva   +4 more
wiley   +1 more source

The Scope and Scale of Clinical Research Accomplished by Rheumatologists Early in Their Careers [PDF]

open access: yes, 2009
[Excerpt] The scope and scale of clinical research is unknown for any medical or surgical specialty beyond snap shots of the broad aims and expenditures of research programs sponsored by federal agencies or the pharmaceutical industry.
Desjardins, Claude   +2 more
core   +1 more source

Evaluation of 6‐Month Knowledge Retention and Satisfaction After Pedagogical Escape Games in Dentistry

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose To evaluate 6‐month knowledge retention and long‐term satisfaction after two pedagogical escape games (PEGs) addressing foundational (3D printing) and clinical (pediatric dentistry) content in a dental curriculum. Methods In this monocentric serial cross‐sectional study, immediate post‑PEG knowledge was assessed in fifth‑year dental ...
Lina Grich   +8 more
wiley   +1 more source

Disease course, frequency of relapses and survival of 73 patients with juvenile or adult dermatomyositis [PDF]

open access: yes, 2005
Objective Our aim is to present the disease course, frequency of relapses and survival of juvenile and adult dermatomyositis (JDM/DM) patients. Methods Analysis was performed using data on 73 patients. The median follow-up for 38 JDM patients was
Balogh, Zsolt   +9 more
core  

Perceived Educational Value of a Self‐Developed 3D‐Printed Pediatric Dentistry Simulator

open access: yesJournal of Dental Education, EarlyView.
ABSTRACT Purpose To design and assess a 3D‐printed pediatric dentistry simulator and to evaluate its perceived educational value and realism through student and expert feedback. Methods A maxillary simulator that is mountable on phantom heads was developed and produced by desktop stereolithography with single‐use inserts, enabling proximal caries ...
Michel Benyamin   +11 more
wiley   +1 more source

Children and adolescents with disorders of gut–brain interaction with comorbid hypermobility and orthostatic intolerance have worse outcomes

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Disorders of gut–brain interaction (DGBI) affect about 40% of children and are often comorbid with hypermobility spectrum disorders (HSDs) and orthostatic intolerance (OI). However, how these comorbidities impact outcomes in pediatric DGBI is not well understood.
Neha Santucci   +6 more
wiley   +1 more source

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