Results 91 to 100 of about 212,517 (305)

Exploring Long-Term Neurocognitive Impact of Pineal Region Tumors: Clinical and Therapeutical Perspectives from a Single-Center Study

Children
Purpose: Pineal region tumors are rare tumors in the pediatric population, typically managed with surgical resection or biopsy, and often with radiation therapy and chemotherapy.
Flavio Panico, Antonio Verrico, Maria Sole Venanzi, Maria Grazia Calevo, Diego Garbossa, Claudia Milanaccio, Gianluca Piatelli, Alessandro Consales   +7 more
doaj   +1 more source

Targeted antiangiogenic agents in combination with cytotoxic chemotherapy in preclinical and clinical studies in sarcoma. [PDF]

, 2016
Sarcomas are a heterogeneous group of mesenchymal malignancies. In recent years, studies have demonstrated that inhibition of angiogenic pathways or disruption of established vasculature can attenuate the growth of sarcomas.
DuBois, Steven G, Matthay, Katherine K, Vo, Kieuhoa T   +2 more
core   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

P348: GENOMIC CHARACTERIZATION OF RELAPSED/REFRACTORY B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA PEDIATRIC PATIENTS UNDERGOING CAR-T TREATMENT IN A SINGLE CENTER

HemaSphere, 2023
Elena Esperanza Cebollada, Clara Vicente Garcés, Anna Alsonso, Esther Cuatrecasas Capdevila, Sandra Andreu, Alba Crespo Carrasco, Mercè Richarte, Sara Montesdeoca, Montserrat Torrebadell, Mireia Camos Guijosa, Susana Rives, Nerea Vega García   +11 more
doaj   +1 more source

QIIME2 enhances multi-amplicon sequencing data analysis: a standardized and validated open-source pipeline for comprehensive 16S rRNA gene profiling

Microbiology Spectrum
Multi-amplicon sequencing is a cost-effective method for profiling multiple regions of the 16S rRNA gene, offering a more comprehensive view of microbial diversity.
Armando G. Licata, Marica Zoppi, Chiara Dossena, Federico Rossignoli, Davide Rizzo, Manuela Marra, Giorgio Gargari, Giacomo Mantegazza, Simone Guglielmetti, Luca Bergamaschi, Olga Nigro, Stefano Chiaravalli, Maura Massimino, Loris De Cecco   +13 more
doaj   +1 more source

Hyperthermia combined with chemotherapy - Biological rationale, clinical application, and treatment results [PDF]

, 1999
There is substantial evidence from preclinical data that the antitumor cytotoxicity of selected chemotherapeutic agents either alone or combined with radiation can be enhanced by appropriate heat exposure (40-44 degrees C) of cells or tumor tissues ...
Issels, Rolf-Dieter
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source