Results 121 to 130 of about 996,187 (255)

Diagnostic Utility of Diffusion-Weighted Imaging in Distinguishing Common Pediatric Posterior Fossa Tumors: A Single Center Retrospective Study

Objective: Pediatric posterior fossa tumors pose diagnostic challenges due to their diverse histopathological features and variable clinical presentations.
Elif Habibe Aktekin, Cigdem Yalcin, Umur Anil Pehlivan, Aylin Gunesli, Ozlem Alkan, Bermal Hasbay   +5 more
core   +1 more source

Modern Imaging Guidelines for 3-D Modeling of Pediatric Solid Tumors: A New Era of Surgical Oncology Operative Planning [PDF]

Background: Three-dimensional (3-D) models are gaining interest for surgical planning in the field of pediatric surgical oncology. The diverse tumor types in pediatric patients and the non-uniform presentation and anatomy make 3D modeling in pediatric ...
Towbin, Alexander J., Erika A. Newman, Dhanashree Rajderkar, Eric Diaz, Brown, Erin G., Mark L. Ryan, Robertson, Daniel J., Lincoln M. Wong, Wong, Lincoln M., Zachary R. Abramson, Christopher Z. Lam, Shah, Nikhil R., Fusco, Joseph C., Nikhil R. Shah, Lam, Christopher Z., Raslan, Osama, Rajderkar, Dhanashree, Davidoff, Andrew M., Ryan, Mark L., Abramson, Zachary R., Diaz, Eric, Alexander J. Towbin, Erin G. Brown, Newman, Erika A., Daniel J. Robertson, Joseph C. Fusco, Williams, Keyonna M., Andrew M. Davidoff, Keyonna M. Williams, Osama Raslan   +29 more
core   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Pediatric brain tumors

Nepal Journal of Neuroscience, 2003
Tumors of the central nervous system are, as a group, the most common solid tumor of childhood. Despite significant advances in the diagnosis and treatment of pediatric malignancies elsewhere in the body, tumor of the brain continue to affect ...
Kevin L. Stevenson, MD
doaj  

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

From benign to malignant: Spectrum of skeletal muscle tumors in pediatric patients – A case series

Indian Journal of Dental Research
Objectives: To demonstrate the biological spectrum of pediatric skeletal muscle tumors by presenting cases of fetal-type rhabdomyoma and embryonal rhabdomyosarcoma.
Sonali Goyal, Sunita Gupta, Sujoy Ghosh
doaj   +1 more source

Molecular diagnosis of pediatric tumors

, 2017
<p>Pediatric tumors are challenging in the context of best diagnosis, treatment, and prognosis. For tumors which have a genetic association or a cancer predisposition syndrome, the prognosis depends on accurate diagnosis.
Tanushri Mukherjee, Rajat Dutta, Soma Mukherjee   +2 more
core   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumors

Nature Communications
Central nervous system (CNS) tumors are the leading cause of pediatric cancer death, and these patients have an increased risk for developing secondary neoplasms.
Min Kyung Lee, Nasim Azizgolshani, Joshua A. Shapiro, Lananh N. Nguyen, Fred W. Kolling, George J. Zanazzi, Hildreth Robert Frost, Brock C. Christensen   +7 more
doaj   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source