Results 31 to 40 of about 996,187 (255)
RNA sequencing (RNA-seq) is a reliable tool for detecting gene fusions in acute leukemia. Multiple bioinformatics pipelines have been developed to analyze RNA-seq data, but an agreed gold standard has not been established. This study aimed to compare the
Clara Vicente-Garcés +19 more
doaj +1 more source
The most common pediatric orbital malignancy in the developed countries is rhabdomyosarcoma. In the developing world, however, the most common orbital malignancies in the pediatric group are not primary malignant tumors, but rather secondary and ...
Karcioglu, Zeynel A +1 more
core +1 more source
Pediatric cancer pathology review from a single institution: Neuropathology expert opinion is essential for accurate diagnosis of pediatric brain tumors [PDF]
Background and objectives: Second pathology review has been reported to improve accuracy in oncologic diagnoses, including pediatric malignancies. We assessed the impact of second review on the diagnosis of pediatric malignancies at a tertiary care ...
Jeha, Sima S. +10 more
core +1 more source
Pursuing Precision: Receptor Tyrosine Kinase Inhibitors for Treatment of Pediatric Solid Tumors
Receptor tyrosine kinases are critical for the growth and proliferation of many different cancers and therefore represent a potential vulnerability that can be therapeutically exploited with small molecule inhibitors. Over forty small molecule inhibitors
Lars M. Wagner, Andrew J. Bellantoni
core +1 more source
Primary Extragonadal Germ Cell Tumors in Klinefelter Syndrome: 10-Years of Experience from a Single Institute [PDF]
Background: Approximately 8% of male patients presenting with primary mediastinal germ cell tumors (GCTs) have Klinefelter syndrome (KS), while patients diagnosed with retroperitoneal GCTs also exhibit a range of chromosomal abnormalities.
안원기 +3 more
core +1 more source
Rare granular cell tumor affecting a 13-year-old boy
Granular cell tumor (GCT) is a rare soft-tissue neoplasm, first described in 1926. GCT often manifests as a single, painless nodule that shows a slow enlargement in the cutaneous, subcutaneous, or submucosal tissues.
S M Balaji, Preetha Balaji
doaj +1 more source
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
This study aimed to compare the efficacy and safety of arthroscopy with physiotherapy or joint lavage in patients with femoroacetabular impingement (FAI).
José María Lamo-Espinosa +3 more
doaj +1 more source
Genetic Predisposition to Solid Pediatric Cancers
Progresses over the past years have extensively improved our capacity to use genome-scale analyses—including high-density genotyping and exome and genome sequencing—to identify the genetic basis of pediatric tumors.
Mario Capasso +10 more
doaj +1 more source
Stemness Correlates Inversely with MHC Class I Expression in Pediatric Small Round Blue Cell Tumors
SIMPLE SUMMARY: Tumors occurring at a young age are distinct from tumors in older individuals, clinically and pathologically. As small round blue cell tumors (SRBCTs), they often show a resemblance to stem cells and immature precursor cells during ...
Kschischo, Maik +9 more
core +1 more source

