Results 31 to 40 of about 996,187 (255)

Fusion InPipe, an integrative pipeline for gene fusion detection from RNA-seq data in acute pediatric leukemia

open access: yesFrontiers in Molecular Biosciences, 2023
RNA sequencing (RNA-seq) is a reliable tool for detecting gene fusions in acute leukemia. Multiple bioinformatics pipelines have been developed to analyze RNA-seq data, but an agreed gold standard has not been established. This study aimed to compare the
Clara Vicente-Garcés   +19 more
doaj   +1 more source

Malignant pediatric tumors

open access: yes, 2015
The most common pediatric orbital malignancy in the developed countries is rhabdomyosarcoma. In the developing world, however, the most common orbital malignancies in the pediatric group are not primary malignant tumors, but rather secondary and ...
Karcioglu, Zeynel A   +1 more
core   +1 more source

Pediatric cancer pathology review from a single institution: Neuropathology expert opinion is essential for accurate diagnosis of pediatric brain tumors [PDF]

open access: yes, 2018
Background and objectives: Second pathology review has been reported to improve accuracy in oncologic diagnoses, including pediatric malignancies. We assessed the impact of second review on the diagnosis of pediatric malignancies at a tertiary care ...
Jeha, Sima S.   +10 more
core   +1 more source

Pursuing Precision: Receptor Tyrosine Kinase Inhibitors for Treatment of Pediatric Solid Tumors

open access: yes, 2021
Receptor tyrosine kinases are critical for the growth and proliferation of many different cancers and therefore represent a potential vulnerability that can be therapeutically exploited with small molecule inhibitors. Over forty small molecule inhibitors
Lars M. Wagner, Andrew J. Bellantoni
core   +1 more source

Primary Extragonadal Germ Cell Tumors in Klinefelter Syndrome: 10-Years of Experience from a Single Institute [PDF]

open access: yes, 2020
Background: Approximately 8% of male patients presenting with primary mediastinal germ cell tumors (GCTs) have Klinefelter syndrome (KS), while patients diagnosed with retroperitoneal GCTs also exhibit a range of chromosomal abnormalities.
안원기   +3 more
core   +1 more source

Rare granular cell tumor affecting a 13-year-old boy

open access: yesIndian Journal of Dental Research, 2018
Granular cell tumor (GCT) is a rare soft-tissue neoplasm, first described in 1926. GCT often manifests as a single, painless nodule that shows a slow enlargement in the cutaneous, subcutaneous, or submucosal tissues.
S M Balaji, Preetha Balaji
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Efficacy and safety of arthroscopy in femoroacetabular impingement syndrome: a systematic review and meta-analysis of randomized clinical trials

open access: yesScientific Reports
This study aimed to compare the efficacy and safety of arthroscopy with physiotherapy or joint lavage in patients with femoroacetabular impingement (FAI).
José María Lamo-Espinosa   +3 more
doaj   +1 more source

Genetic Predisposition to Solid Pediatric Cancers

open access: yesFrontiers in Oncology, 2020
Progresses over the past years have extensively improved our capacity to use genome-scale analyses—including high-density genotyping and exome and genome sequencing—to identify the genetic basis of pediatric tumors.
Mario Capasso   +10 more
doaj   +1 more source

Stemness Correlates Inversely with MHC Class I Expression in Pediatric Small Round Blue Cell Tumors

open access: yes, 2022
SIMPLE SUMMARY: Tumors occurring at a young age are distinct from tumors in older individuals, clinically and pathologically. As small round blue cell tumors (SRBCTs), they often show a resemblance to stem cells and immature precursor cells during ...
Kschischo, Maik   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy