Results 21 to 30 of about 212,517 (305)

Technical Validation and Clinical Utility of an NGS Targeted Panel to Improve Molecular Characterization of Pediatric Acute Leukemia

Frontiers in Molecular Biosciences, 2022
Development of next-generation sequencing (NGS) has provided useful genetic information to redefine diagnostic, prognostic, and therapeutic strategies for the management of acute leukemia (AL).
Clara Vicente-Garcés, Clara Vicente-Garcés, Elena Esperanza-Cebollada, Elena Esperanza-Cebollada, Sara Montesdeoca, Sara Montesdeoca, Montserrat Torrebadell, Montserrat Torrebadell, Montserrat Torrebadell, Susana Rives, Susana Rives, Susana Rives, José Luis Dapena, José Luis Dapena, Albert Català, Albert Català, Albert Català, Nuria Conde, Nuria Conde, Mireia Camós, Mireia Camós, Mireia Camós, Nerea Vega-García, Nerea Vega-García   +23 more
doaj   +1 more source

Epigenomics and immunotherapeutic advances in pediatric brain tumors

npj Precision Oncology, 2021
Brain tumors are the leading cause of childhood cancer-related deaths. Similar to adult brain tumors, pediatric brain tumors are classified based on histopathological evaluations. However, pediatric brain tumors are often histologically inconsistent with
Malak Abedalthagafi, Nahla Mobark, May Al-Rashed, Musa AlHarbi   +3 more
doaj   +1 more source

Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody

Molecular Therapy: Oncolytics, 2023
Phosphatase of regenerating liver 3 (PRL3) is a specific tumor antigen overexpressed in a broad range of adult cancer types. However, its physiological expression in pediatric embryonal and mesenchymal tumors and its association with clinical outcomes in
Amos Hong Pheng Loh, Min Thura, Abhishek Gupta, Sheng Hui Tan, Kelvin Kam Yew Kuan, Koon Hwee Ang, Khurshid Merchant, Kenneth Tou En Chang, Hui Yi Yon, Yong Chen, Mathew Hern Wang Cheng, Arjandas Mahadev, Matthew Chau Hsien Ng, Michaela Su-Fern Seng, Prasad Iyer, Pei Ling Chia, Shui Yen Soh, Qi Zeng   +17 more
doaj   +1 more source

Total hepatectomy and liver transplant for hepatocellular adenomatosis and focal nodular hyperplasia. [PDF]

, 1992
Extensive hepatocellular adenomatosis (HA) and focal nodular hyperplasia (FNH) represent a proliferation of hepatic cells that occurs most frequently in women.
Bronsther, O, Iwatsuki, S, Marino, IR, Scantlebury, VP, Starzl, TE   +4 more
core   +4 more sources

The role of particle radiotherapy in the treatment of skull base tumors

Frontiers in Oncology, 2023
The skull base is an anatomically and functionally critical area surrounded by vital structures such as the brainstem, the spinal cord, blood vessels, and cranial nerves.
Alberto Iannalfi, Giulia Riva, Lucia Ciccone, Ester Orlandi   +3 more
doaj   +1 more source

The Current Status and Future Potential of Theranostics to Diagnose and Treat Childhood Cancer

Frontiers in Oncology, 2020
In theranostics (i.e., therapy and diagnostics) radiopharmaceuticals are used for both therapeutic and diagnostic purposes by targeting one specific tumor receptor.
Alex J. Poot, Alex J. Poot, Marnix G. E. H. Lam, Max M. van Noesel   +3 more
doaj   +1 more source

Measurement of Apparent Diffusion Coefficient (ADC) Values of Ependymoma and Medulloblastoma Tumors: a Patient-based Study [PDF]

Journal of Biomedical Physics and Engineering, 2021
Background: Some brain tumors such as ependymoma and Medulloblastoma have similar MR images which may result to undifferentiated them from each other.
H Taheri, M B Tavakoli
doaj   +1 more source

Giant pediatric de novo parapharyngeal space pleomorphic adenoma: excision by semi trans-parotid cervical approach

The Egyptian Journal of Otolaryngology, 2023
Background Parapharyngeal Space tumors are rare tumors of the head and neck. They most commonly arise from the deep lobe of the parotid gland. Most of these tumors are in seen in adults and de novo origin from the minor salivary glands is extremely rare.
Abhishek Bhardwaj, Suji PS, Rachit Sood, Manu Malhotra, Madhu Priya, Rosy Saikia   +5 more
doaj   +1 more source

Management of germ cell tumors in children: Approaches to cure [PDF]

, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G., Göbel, U., Haas, R. J., Schmidt, P., Schneider, D. T.   +4 more
core   +1 more source

Pediatric extraspinal sacrococcygeal ependymoma (ESE): an Italian AIEOP experience of six cases and literature review [PDF]

, 2018
Background: Primary pediatric extraspinal sacrococcygeal ependymoma (ESE) is a very rare disease, poorly described in literature, whose diagnostic, therapeutic, and follow-up approach is still controversial.
Antonelli, Manila, Biassoni, Veronica, Cesaro, Simone, Gandola, Lorenza, Modena, Piergiorgio, Pierani, Paolo, Schiavello, Elisabetta   +6 more
core   +1 more source