Results 21 to 30 of about 996,187 (255)

BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors

, 2022
BRAF is a component of the MAPK and PI3K/AKT/mTOR pathways that play a crucial role in cellular proliferation, differentiation, migration, and angiogenesis.
Attinà, Giorgio, Mastrangelo, Stefano, Triarico, Silvia, Maurizi, Palma, Dario Talloa, Agresti, Pierpaolo, Pierpaolo Agresti, Antonio Ruggiero, Silvia Triarico, Palma Maurizi, Talloa, Dario, Stefano Mastrangelo, Giorgio Attinà, Ruggiero, Antonio, Alberto Romano, Romano, Alberto   +15 more
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Large orbital glial heterotopia- A rare entity

Indian Journal of Pathology and Microbiology, 2022
A 15-month-old child was brought to the ophthalmology outpatient department with his parents complaining of a large mass located on the nasal side of his right eye since birth. On examination, an irregular mass was seen to be located on the nasal side of
Sujeeth Modaboyina, Akshaya Balaji, Sahil Agrawal, Deepsekhar Das, Seema Sen   +4 more
doaj   +1 more source

Challenges and opportunities for managing pediatric central nervous system tumors in China [PDF]

, 2020
Central nervous system (CNS) tumors represent the most deadly cancer in pediatric age group. In China, thousands of children are diagnosed with CNS tumors every year. Despite the improving socioeconomic status and availability of medical expertise within
Krull, L, Yang, B, Bo Yang, Kejun He, Daniel C. Moreira, Godfrey Chi‐Fung Chan, Xiaofei Sun, Anthony Pak‐Yin Liu, Xiaojun Yuan, Chenchen Sun, Chan, GCF, Ma, X, Yuan, X, Moreira, DC, Gao, Y, Chenran Zhang, Sun, C, Lisa Krull, Yijin Gao, Ibrahim A. Qaddoumi, Xiaoli Ma, Liu, APY, Zhang, C, Sun, X, Qaddoumi, IA, He, K   +25 more
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Succinate dehydrogenase (SDH)-deficient renal carcinoma:a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients [PDF]

, 2014
Succinate dehydrogenase (SDH)-deficient renal carcinoma has been accepted as a provisional entity in the 2013 International Society of Urological Pathology Vancouver Classification.
Sedivcová, Monika, Yu, Darryl, Papathomas, Thomas, Niemeijer, Nicolasine D., Przybycin, Christopher, Nicoll, Katherine D, Paik, Julie, Miettinen, Markku, Yong, Jim L., Kedziora, Andrew, Andresen, Per Arne, Hes, Ondrej, Toon, Christopher W., Robinson, Bruce G, Corssmit, Eleonora P M, Michal, Michal, Chou, Angela, Hills, Kirsten, Nicoll, Katherine D., Clarkson, Adele, Clifton-bligh, Roderick J., Yong, Jim L, Maclean, Fiona, Yilmaz, Asli, Vlatkovic, Ljiljana, Niemeijer, Nicolasine D, Hartmann, Arndt, Sibony, Mathilde, Agaimy, Abbas, McKenney, Jesse K, Robinson, Bruce G., Van Leenders, Geert J.l.h., Chow, Chung W., Sioson, Loretta, Mckenney, Jesse K., Corssmit, Eleonora P.m., Tan, Puay Hoon, van Leenders, Geert J L H, Yakirevich, Evgeny, Trpkov, Kiril, Benn, Diana E., Gill, Anthony J., Chow, Chung W, Watson, Nicole, Fleming, Stewart, Magi-Galluzzi, Cristina, Clifton-Bligh, Roderick J   +46 more
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Neuroblastoma of the Urinary Bladder in an Infant

European Journal of Pediatric Surgery Reports, 2019
As it originates from neural crest cells, Neuroblastoma (NBL) can arise anywhere along the sympathetic chain. However, its occurrence in the urinary bladder (UB) is extremely rare.
Ahmed Mohamed, Quentin Campbell-Hewson, Hany O. S. Gabra   +2 more
doaj   +1 more source

How to target apoptosis signaling pathways for the treatment of pediatric cancers [PDF]

, 2013
Apoptosis represents one of the most important forms of cell death in higher organisms and is typically dysregulated in human cancers, including pediatric tumors.
Simone Fulda, Simone eFulda, Fulda, Simone   +2 more
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Malignant pediatric tumors in : Orbital Tumors

, 2005
Part V Pediatric Orbital Tumors and Pseudotumors 26 .
HADJISTILIANOU, THEODORA, KARCIOGLU Z.
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Child-related characteristics predicting subsequent health-related quality of life in 8- to 14-year-old children with and without cerebellar tumors: a prospective longitudinal study

, 2014
BackgroundWe identified child-related determinants of health-related quality of life (HRQoL) in children aged 8–14 years who were treated for 2 common types of pediatric brain tumors.
Kennedy, Colin R., Christina Liossi, Culliford, David, Colin R. Kennedy, Kim S. Bull, David Culliford, Liossi, Christina, Peacock, Janet L., Janet L. Peacock, Bull, Kim S.   +9 more
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A molecular map of mesenchymal tumors [PDF]

, 2005
Background: Bone and soft tissue tumors represent a diverse group of neoplasms thought to derive from cells of the mesenchyme or neural crest. Histological diagnosis is challenging due to the poor or heterogenous differentiation of many tumors, resulting
Flanagan, AM, Guiliano, D, Boshoff, C, McLean, S, Frow, R, Sebire, N, Henderson, SR, Stephen R Henderson, Nick Athanasou, Vujovic, S, Anderson, J, Athanasou, N, John Anderson, Neil Sebire, David Guiliano, Sean McLean, Nadege Presneau, Richard Frow, Jeremy Whelan, Whelan, J, Adrienne M Flanagan, Presneau, N, Sonja Vujovic, Chris Boshoff   +23 more
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Rhabdomyosarcoma of the breast: Report of two cases with the review of literature

Journal of Indian Association of Pediatric Surgeons, 2016
Rhabdomyosarcoma (RMS) is a common soft-tissue neoplasm in the pediatric age group. Common locations are head and neck, genitourinary areas, trunk, and extremities. Two pathologic variants of this malignancy are embryonal and alveolar. The involvement of
Nizamudheen M Pareekutty, Monica Bhagat, Tushar Vora, Sajid S Qureshi   +3 more
doaj   +1 more source