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Pediatric Spinal Tumors

open access: yesPediatric Neurology Briefs, 2001
The clinical outcome and surgical treatment of 34 pediatric spinal tumors seen over an 18-year period (1981-1999) were analysed in a retrospective study at the Neurosurgical University Hospital of Frankfurt am Main, Germany.
J Gordon Millichap
doaj   +4 more sources

Pediatric brain tumors

open access: yesCa-A Cancer Journal for Clinicians, 1993
Brain tumors are the second most common cancer of children. Although children with brain tumors have a better prognosis than adults, treatment presents special problems, including possible damage to the developing brain. This article reviews the classification, symptoms, diagnosis, and treatment of pediatric brain tumors.
A L Albright
exaly   +3 more sources

Incidence and risk factors for stroke after hip fracture: a meta-analysis

open access: yesScientific Reports, 2023
Hip fractures represent a high burden and are associated with mortality in up to 30% of the cases. Stroke complications can be devastating and increase mortality and disability in elderly patients.
José María Lamo-Espinosa   +3 more
doaj   +1 more source

VRK3 depletion induces cell cycle arrest and metabolic reprogramming of pontine diffuse midline glioma - H3K27 altered cells

open access: yesFrontiers in Oncology, 2023
We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome. The aim of the present study was to elucidate the mechanisms by which VRK3 depletion impact DMG-H3K27M cell fitness.
Virginie Menez   +18 more
doaj   +1 more source

RETRACTED ARTICLE: Efficacy and safety of arthroscopy in femoroacetabular impingement syndrome: a systematic review and meta-analysis of randomized clinical trials

open access: yesScientific Reports, 2023
This study aimed to compare the efficacy and safety of arthroscopy with physiotherapy or joint lavage in patients with femoroacetabular impingement (FAI).
José María Lamo-Espinosa   +3 more
doaj   +1 more source

Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma

open access: yesFrontiers in Immunology, 2023
IntroductionCellular senescence (CS) plays a critical role in cancer development, including clear cell renal cell carcinoma (ccRCC). Traditional RNA sequencing cannot detect precise molecular composition changes within tumors. This study aimed to analyze
Qiming Gong   +5 more
doaj   +1 more source

Measurement of Apparent Diffusion Coefficient (ADC) Values of Ependymoma and Medulloblastoma Tumors: a Patient-based Study [PDF]

open access: yesJournal of Biomedical Physics and Engineering, 2021
Background: Some brain tumors such as ependymoma and Medulloblastoma have similar MR images which may result to undifferentiated them from each other.
H Taheri, M B Tavakoli
doaj   +1 more source

Pediatric genitourinary tumors [PDF]

open access: yesCurrent Opinion in Oncology, 2009
We will review the 2007/2008 literature on pediatric genitourinary tumors.Newly identified constitutional epigenetic defects in Wilms tumor genes extend the understanding of Wilms tumor risk in children lacking syndromic features, and add to the complexity of the pathogenesis of these tumor suppressor genes.
Sharon M, Castellino   +2 more
openaire   +2 more sources

Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody

open access: yesMolecular Therapy: Oncolytics, 2023
Phosphatase of regenerating liver 3 (PRL3) is a specific tumor antigen overexpressed in a broad range of adult cancer types. However, its physiological expression in pediatric embryonal and mesenchymal tumors and its association with clinical outcomes in
Amos Hong Pheng Loh   +17 more
doaj   +1 more source

The role of particle radiotherapy in the treatment of skull base tumors

open access: yesFrontiers in Oncology, 2023
The skull base is an anatomically and functionally critical area surrounded by vital structures such as the brainstem, the spinal cord, blood vessels, and cranial nerves.
Alberto Iannalfi   +3 more
doaj   +1 more source

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