Results 101 to 110 of about 1,197,190 (411)

FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier, Giulia F. Del Gobbo, Layla Mackay, Erika Wall, Madeline Couse, Laura M. McDonell, Mireille Cloutier, Matt C. Danzi, Jodi Warman‐Chardon, Pierre R. Bourque, Oksana Suchowersky, Alan Mears, Luke Seldenthuis, Wendy Mears, Laura Larrigan, Alexandre White‐Brown, Gerald Pfeffer, Dennis E. Bulman, David Dyment, Care4Rare Canada Consortium, Kym M. Boycott   +20 more
wiley   +1 more source

Treatment of Allergic Rhinitis With Desloratadine: Results of a Multinational Observational Study in the Middle East Gulf Region

World Allergy Organization Journal, 2011
Background Allergic rhinitis (AR) affects up to 36% of the population in the Middle East Gulf States. The second-generation nonsedating antihistamine desloratadine has demonstrated safety and efficacy in the treatment of AR; however, few studies have ...
Tamer M.H. Adham, MD(Pediatrics), MRCPCH(London)
doaj  

Cardiopulmonary Exercise Testing in Pediatrics

Annals of the American Thoracic Society, 2017
&NA; Aerobic fitness is an important determinant of overall health. Higher aerobic fitness has been associated with many health benefits. Because myocardial ischemia is rare in children, indications for exercise testing differ in children compared with ...
T. Takken, B. Bongers, M. van Brussel, E. Haapala, E. Hulzebos   +4 more
semanticscholar   +1 more source

Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi, Zitian Tang, Wendy Dong, Jenna Ulibarri, Elvisa Mehinovic, Simone Thomas, Ahmet Höke, Sheng Chih Jin   +7 more
wiley   +1 more source

Profile and scientific production of Brazilian National Council of Technological and Scientific Development researchers in Pediatrics

Revista Paulista de Pediatria, 2013
OBJECTIVE: To evaluate the profile and the scientific production of researchers in Pediatrics with scholarship from the National Counsel of Technological and Scientific Development.
Maria Christina L. Oliveira, Daniella Reis B. Martelli, Sergio Veloso Pinheiro, Debora Marques Miranda, Isabel Gomes Quirino, Barbara Gusmão L. Leite, Enrico Antonio Colosimo, Ana Cristina S. e Silva, Hercílio Martelli-Júnior, Eduardo Araujo Oliveira   +9 more
doaj   +1 more source

3D Printing and 3D Bioprinting in Pediatrics

Bioengineering, 2017
Additive manufacturing, commonly referred to as 3D printing, is a technology that builds three-dimensional structures and components layer by layer. Bioprinting is the use of 3D printing technology to fabricate tissue constructs for regenerative medicine
S. Vijayavenkataraman, J. Fuh, W. Lu
semanticscholar   +1 more source

Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized trial enrolled infants aged 2–14 months with new‐onset IESS, randomly assigned them (1:1) to receive either
Rachata Boonkrongsak, Kantapon Trongkamolchai, Sirorat Suwannachote, Somjit Sri‐Udomkajorn, Raviwan Wittawassamrankul, Ravindra Arya, Kullasate Sakpichaisakul   +6 more
wiley   +1 more source

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

Arthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner, Anna Shmagel, Gerd Horneff, Ivan Foeldvari, Jordi Antón, Athimalaipet V. Ramanan, Yuli Qian, Kristina Unnebrink, Shuai Hao, Heidi S. Camp, Nasser Khan, Wei Liu, Mohamed‐Eslam F. Mohamed   +12 more
wiley   +1 more source

Factors And Experiences That Influence Physical Therapy Students\u27 Considerations To Practice Pediatric Physical Therapy [PDF]

, 2019
The purpose of this quantitative non-experimental research study was to explore the difference that life experiences, educational experiences, and clinical experiences made on physical therapy students’ considerations to practice ...
Elbert, Amy Joleen
core   +1 more source

Priority Musculoskeletal Health Research Questions for People With Generalized Joint Hypermobility: An International Delphi Study

Arthritis Care &Research, EarlyView.
Objective This study aimed to identify the top 10 international research priorities for musculoskeletal health of people with generalized joint hypermobility. Methods A three‐round Delphi method using an online survey was implemented. Three participant stakeholder groups were eligible for inclusion: (1) people with lived experience of joint ...
Sara Habibian, Verity Pacey, Cliffton Chan, Alan J. Hakim, Cylie M. Williams   +4 more
wiley   +1 more source