Results 191 to 200 of about 626,236 (265)
Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs, Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang +6 morewiley +1 more sourceA cross-sectional examination of immune adaptations during pregnancy in the ECHO Cohort. [PDF]
Front ImmunolBanker SM, Shapiro-Thompson R, Sinsel S, Ghassabian A, Douglas C, Nelson ME, Peterson LA, Thyagarajan B, Morales S, Hockett CW, Elliott AJ, Giamberardino SN, Shuffrey LC. +12 moreeuropepmc +1 more sourceMass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin +11 morewiley +1 more sourceRare <i>KDR</i> Variants Define a Distinct Genetic Contribution to Congenital Heart Disease. [PDF]
Circ Genom Precis MedLadha FA, Avillach P, Opotowsky AR, Nael A, Brueckner M, Chung WK, Cnota JF, Gelb BD, Lewis M, Liu C, Roberts AE, Seidman CE, Seidman JG, Tristani-Firouzi M, Wagner M, Newburger JW, Kim Y, Morton SU. +17 moreeuropepmc +1 more sourceGHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu +24 morewiley +1 more sourceCerebral Oximetry in Extremely Preterm Infants: 2-Year Follow-Up of the SafeBoosC-III Randomized Clinical Trial.
JAMA PediatrRasmussen MIS, Hansen ML, Pellicer A, Hyttel-Sørensen S, Ergenekon E, Szczapa T, Hagmann C, Naulaers G, Mintzer J, Fumagalli M, Dimitriou G, Dempsey E, Tkaczyk J, Fredly S, Heuchan AM, Pichler G, Fuchs H, Nesargi S, Hahn GH, Piris-Borregas S, Širc J, Alsina-Casanova M, Stocker M, Ozkan H, Sarafidis K, Kraus NJ, Karen T, Rzepecka-Weglarz B, Oguz SS, Thewissen L, Arruza L, Memisoglu AC, Del Rio Florentino R, Baserga M, Maton P, Schneider J, de Las Cuevas MI, Hedegaard SS, Zafra P, Bender L, Farquharson S, Ochoda-Mazur A, Lecart C, El-Khuffash A, Chathasaigh CN, Miletin J, Papathoma E, Vesoulis Z, Serrao F, SafeBoosC-III Follow-Up Writing Group for the SafeBoosC-III Follow-Up Collaborator Group, Cornette L, Yasa B, Klamer A, Barcos-Munoz F, Boetti T, Cetinkaya M, Montasser M, Hatzidaki E, Bokiniec R, Marciniak S, Chalak L, Rao SA, Sadowska-Krawczenko I, Serrano-Viñuales I, Krolak-Olejnik B, Plomgaard AM, Hansen BM, Olsen MH, Gluud C, Jakobsen JC, Greisen G. +70 moreeuropepmc +1 more sourceCD71 as an independent prognostic factor in pediatric B-ALL: a regional multicenter retrospective study in Southern China (SCCLG-ALL-2016). [PDF]
Ther Adv Med OncolChen XF, Jia WG, Liu Y, Liu LL, Long XJ, Yu LH, Kuang WY, Cai Y, Liao LH, Wu BY, Li QR, Fu Y, Ren HY, Chen GH, Wang LN, Wang J, Zhong N, Zhen ZJ, Mai HR, Kong XL, Chen JJ, Ling YY, Wen C, He YY, Tang YL. +24 moreeuropepmc +1 more source