Results 61 to 70 of about 863,421 (266)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Twelve-Month Outcomes of the First 1000 Days Program on Infant Weight Status

, 2021
OBJECTIVES: To examine the effects of the First 1000 Days intervention on the prevalence of infant overweight and maternal postpartum weight retention and care.
Blake-Lamb, Tiffany, Roche, Brianna, Matathia, Sarah, Cheng, Erika R., Taveras, Elsie M., Price, Sarah N., Boudreau, Alexy Arauz, Luo, Mandy, Perkins, Meghan E., Kotelchuck, Milton   +9 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Rating Scales in Attention Deficit Disorder

Pediatric Neurology Briefs, 1989
A comparison of parent, teacher, and child performance rating scales in the diagnosis and follow-up of methylphenidate treated children with ADDH is reported from Developmental Pediatrics, San Antonio, TX; Department of Pediatrics, Madigan Army Medical ...
J Gordon Millichap
doaj   +1 more source

Characteristics Associated with Confidential Consultation for Adolescents in Primary Care

, 2018
OBJECTIVE: To examine how provider report of confidential consultation in the electronic health record is associated with adolescent characteristics, health risk factors, and provider training.
Fangqian Ouyang, Rebekah L. Williams, Wanzhu Tu, Downs, Stephen M., Dillon J. Etter, Tu, Wanzhu, Amy Lewis Gilbert, Matthew C. Aalsma, Aalsma, Matthew C., Williams, Rebekah L., Hall, James A., McCord, Allison L., Etter, Dillon J., Allison L. McCord, James A. Hall, Gilbert, Amy Lewis, Ouyang, Fangqian, Stephen M. Downs   +17 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Vitamin D [] Insufficiency is Associated With Childhood Asthma: Recent Case-Control Findings From Bangladesh

Global Pediatric Health
Objectives. To evaluate the interaction between childhood asthma and S. 25(OH) cholecalciferol among Bangladeshi children. Methods. This case control study was conducted in child asthma clinic, Bangladesh Shishu Hospital Institute during March-August ...
Nabila Tabassum MBBS, FCPS (Pediatrics), MRCPCH, Kazi Selim Anwar MD, M.Phil, Probir Kumar Sarkar MBBS, MCPS (Pediatrics), DCH, FCPS (Pediatrics), A. R. M. Luthful Kabir MBBS, FCPS (Pediatrics), Md. Abid Hossain Mollah MBBS, FCPS (Pediatrics), Dip-Med Ed, FACP, FRCP, Dipa Saha MBBS, FCPS (Pediatric Neurology), Md. Jahangir Alam MBBS, DCH, MCPS (Pediatrics), FCPS (Pediatrics), Mohammod Jobayer Chisti MBBS, MMed (Pediatrics), PhD (Pediatric Respiratory Medicine)   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source