Results 71 to 80 of about 1,251,614 (342)

The long journey toward improving children’s health: from ‘Korean Journal of Pediatrics’ to ‘Clinical and Experimental Pediatrics’ [PDF]

, 2020
Man Yong Han, Yeong-Ho Rha, Chong-Woo Bae, Baik‐Lin Eun   +3 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Profile and scientific production of Brazilian National Council of Technological and Scientific Development researchers in Pediatrics

Revista Paulista de Pediatria, 2013
OBJECTIVE: To evaluate the profile and the scientific production of researchers in Pediatrics with scholarship from the National Counsel of Technological and Scientific Development.
Maria Christina L. Oliveira, Daniella Reis B. Martelli, Sergio Veloso Pinheiro, Debora Marques Miranda, Isabel Gomes Quirino, Barbara Gusmão L. Leite, Enrico Antonio Colosimo, Ana Cristina S. e Silva, Hercílio Martelli-Júnior, Eduardo Araujo Oliveira   +9 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Rapid tests and urine sampling techniques for the diagnosis of urinary tract infection (UTI) in children under five years: a systematic review [PDF]

, 2005
Background: Urinary tract infection (UTI) is one of the most common sources of infection in children under five. Prompt diagnosis and treatment is important to reduce the risk of renal scarring.
A Doley, A Hoberman, A Hoberman, A Hoberman, AG Weinberg, AM Rodriguez Caballero, AS Aronson, B Bulloch, B Lejeune, B Schersten, C Villanustre Ordonez, CB Begg, CE Armengol, CE Armengol, CM Kunin, CV Pryles, D Vickers, DS Lin, DS Lin, EB Mendez, FJ Marsik, FY Anad, G Schreiter, G Vangone, GR Lockhart, GS Liptak, H Braude, H Saxena, H Tahirovic, HA Cohen, Ian Watt, IJ Ramage, J Benito Fernandez, J Benito Fernandez, J Labbe, J Larcombe, J Matthai, J Parmington, J Pylkkanen, J Rodriguez Cervilla, J Steurer, J Steurer, J Todd, J Upadhyay, J Wiggelinkhuizen, JA Lohr, JD Hardy, JL Fleiss, JM Littlewood, Jos Kleijnen, Julie Cooper, K Dickersin, KN Shaw, KN Shaw, L Huicho, L Kohler, LE Moses, LS Palmer, M Demi, M Farrell, M Giraldez, M Hiraoka, M Marret, MA Santos, Marie Westwood, MH Gorelick, MN Woodward, N Sharief, P Whiting, PC Boreland, PD Holland, Penny Whiting, PMM Bossuyt, PS Dayan, PS Dayan, R Bachur, R DerSimonian, R Lagos Zuccone, R Manson, RD Craver, RD Wammanda, RE Morton, RF Galbraith, RS Fennell, S Arslan, S Dosa, S Feasey, SJ Vernon, SM Downs, T Ahmad, VN Purwar, Y Waisman   +91 more
core   +3 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Immunization During the COVID-19 Pandemic: Recommendations From Indian Academy of Pediatrics Advisory Committee on Vaccines and Immunization Practices [PDF]

, 2020
Srinivas G. Kasi, Shashi Kant Dhir, Sanjay Verma, Harish Pemde, Sundaram Balasubramanian, Sunil Kumar Agarwalla, Abhay Shah, S Shivananda, Sanjay Marathe, Kripasindhu Chatarjee, Sanjay Srirampur, Srinivas Kalyani, Bakul Jayant Parekh, G. V. Basavaraja, Piyush Gupta   +14 more
openalex   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

Detection of KIT mutations in core binding factor acute myeloid leukemia

Leukemia Research Reports, 2018
We have investigated the frequency and the effect of KIT mutations on the outcome of patients with CBF-AML. 69 patients (34 pediatrics and 35 adults) with CBF-AML were enrolled in the study. The frequency of KIT mutations was higher in adults compared to
Passant Badr, Ghada M Elsayed, Dalia Negm Eldin, Bahia Y Riad, Nayera Hamdy   +4 more
doaj   +1 more source

Keys to academic success for under-represented minority young investigators: recommendations from the Research in Academic Pediatrics Initiative on Diversity (RAPID) National Advisory Committee. [PDF]

, 2019
BackgroundAlthough Latinos, African-Americans, and American Indians/Alaska Natives comprise 34% of Americans, these under-represented minorities (URMs) account for only 7% of US medical-school faculty.
DeBaun, Michael R, Flores, Glenn, Fuentes-Afflick, Elena, Jones, V Faye, Mendoza, Fernando S, Mendoza, Jason A, Raphael, Jean L, Wang, C Jason   +7 more
core   +2 more sources