Results 41 to 50 of about 101,430 (312)

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

The Bony Density of the Pedicle Plays a More Significant Role in the Screw Anchorage Ability Than Other Regions of the Screw Trajectory

Orthopaedic Surgery
Objective Osteoporosis is a crucial risk factor for screw loosening. Our studies indicate that the bone mineral density (BMD) in the screw trajectory is a better predictor of screw loosening than the BMD of the lumbar spine or the screw insertion ...
Zan Chen, Yue Chen, Jiajun Zhou, Yanwei He, Jingchi Li   +4 more
doaj   +1 more source

Pedicled Mucosal Flap of the Uvula: An Unusual Cause of Chronic Cough in an Adult

Philippine Journal of Otolaryngology Head and Neck Surgery, 2007
Objective: To describe a case of chronic cough due to pedicled uvular mucosal flap Design: Case report. Setting: A tertiary military hospital Patient: One (1) Result: A mucosal flap was seen arising from the uvula on oropharyngeal examination
Murat Enoz
doaj   +1 more source

Comparison of the early and late postoperative results in cases with pedicled transverse rectus abdominis musculocutaneous flap breast reconstruction: Twenty-year follow-up

Turkish Journal of Plastic Surgery, 2020
Background: The TRAM flap has proven to be the autogenous tissue of choice for breast reconstruction. The progressive improvement of the aesthetic results in long-term follow-up of patients with well-executed TRAM flap breast reconstructions is observed ...
Aret Cerci Ozkan, Orhan Cizmeci, Hulya Aydin, Ufuk Emekli, Burcu Celet Ozden, Burcak Tumerdem Ulug   +5 more
doaj   +1 more source

Bcl-xL-mediated remodeling of rod and cone synaptic mitochondria after postnatal lead exposure: electron microscopy, tomography and oxygen consumption. [PDF]

, 2012
PurposePostnatal lead exposure produces rod-selective and Bax-mediated apoptosis, decreased scotopic electroretinograms (ERGs), and scotopic and mesopic vision deficits in humans and/or experimental animals.
Ellisman, Mark H, Fox, Donald A, Johnson, Jerry E, Perez, Alex, Perkins, Guy A, Scott, Ray   +5 more
core   +1 more source

Simultaneous reconstruction of the oral commissure, lip and buccal mucosa with microvascular transfer of combined first-second toe web and dorsalis pedis flap [PDF]

, 2016
The reconstruction of oral commissure, lip and mucosa defects following tumour resection is a challenging task to the reconstructive surgeon owing to the increasing aesthetic and functional demands.
Chen, Hung-Chi, Ciudad, Pedro, Maruccia, Michele, Sapountzis, Stamatis   +3 more
core   +1 more source

Bona Fide Intersegmental Plane Hepatectomy Along the Glissonean Branches (BIPHG)

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT This review traces the author's personal journey over three decades in the evolution of liver resection techniques, culminating in the proposal of the Bona Fide Intersegmental Plane Hepatectomy Along Glissonean Branches (BIPHG). Beginning with pioneering experiences in laparoscopic and robotic liver surgeries, the author highlights key ...
Go Wakabayashi, Taiga Wakabayashi
wiley   +1 more source

Venous congestion in pedicled flaps for reconstruction of complex soft-tissue defects. Our experience [PDF]

Journal of Biomedical & Clinical Research
We present three cases of reconstruction of complex skin defects using pedicled flaps (gracilis, pectoralis major, and TRAM), all of which postoperatively exhibited venous congestion, characterized by cyanosis, edema, and dark bleeding on pinprick. While
Kaloyan Tonev, Zhivko Dimitrov, Toni Stoyanov   +2 more
doaj   +3 more sources

Where to find facial artery perforators: a reference point [PDF]

, 2010
Reconstructive surgery of the midface using facial artery perforator (FAP) flaps is being used more frequently now as it has been reported to provide better aesthetic results and reduce a traditional two-stage procedure to a one-stage technique.
Fogg, Q., Ng, Z.Y., Shoaib, T.
core   +1 more source

Robotic Versus Laparoscopic Anatomic Liver Resection: Comparison of Perioperative Outcomes—A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
Minimally invasive anatomic liver resection (AR) including major hepatectomy and liver parenchyma‐sparing AR is technically complex and demanding. This systematic review with meta‐analysis including 15 studies comparing 2042 robotic AR and 2129 laparoscopic AR patients demonstrated largely comparable perioperative outcomes and partly better outcomes ...
Yutaro Kato, Atsushi Sugioka, Hiroyuki Kato, Akihiko Horiguchi   +3 more
wiley   +1 more source