Results 111 to 120 of about 287,824 (375)
The challenges of pedigree dog health: approaches to combating inherited disease
Canine Genetics and Epidemiology, 2015 The issue of inherited disorders and poor health in pedigree dogs has been widely discussed in recent years. With the advent of genome-wide sequencing technologies and the increasing development of new diagnostic DNA disease tests, the full extent and ...
L. Farrell +4 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Reliability of pedigree-based and genomic evaluations in selected populations
Genetics Selection Evolution, 2015 Reliability is an important parameter in breeding. It measures the precision of estimated breeding values (EBV) and, thus, potential response to selection on those EBV.
G. Gorjanc, P. Bijma, J. Hickey
semanticscholar +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
FEBS Open Bio, EarlyView.The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Relationships among quantitative traits in F3, F4 and F5 wheat hybrids obtained by pedigree and bulk selection [PDF]
Selekcija i Semenarstvo, 2010 Relationships among quantitative traits of wheat were analyzed in parents and their F3, F4 and F5 hybrids. Three female parents (Briscard, Carifen 12 and Rescler) were crossed with two male parents (Francuska and PKB-Prelivka). Same crosses were repeated
Janković Snežana +2 more
doaj
Establishing Ancestry through Pedigree of a Village with High Prevalence of Hearing-impaired
Journal of Indian Speech Language & Hearing Association, 2017 Introduction Population-based surveys into the cause of deafness have consistently shown that a high percentage (50%) of childhood deafness can be attributed to genetic causes.
Sunil Kumar Raina +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
Pedigree-Based Deciphering of Genome-Wide Conserved Patterns in an Elite Potato Parental Line
Frontiers in Plant Science, 2018 Elite parental lines are more likely to breed fine varieties, but knowledge about elite parents and their genetic backgrounds is limited. In this paper, we investigated the pedigree relationships of potato varieties bred worldwide and in China.
Xiaochuan Li +9 more
doaj +1 more source
Trends in genetic diversity for all Kennel Club registered pedigree dog breeds
Canine Genetics and Epidemiology, 2015 BackgroundInbreeding is inevitable in closed populations with a finite number of ancestors and where there is selection. Therefore, management of the rate of inbreeding at sustainable levels is required to avoid the associated detrimental effects of ...
T. Lewis, B. M. Abhayaratne, S. Blott
semanticscholar +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source