Results 91 to 100 of about 116,425 (280)

Pedigree-Based Deciphering of Genome-Wide Conserved Patterns in an Elite Potato Parental Line

open access: yesFrontiers in Plant Science, 2018
Elite parental lines are more likely to breed fine varieties, but knowledge about elite parents and their genetic backgrounds is limited. In this paper, we investigated the pedigree relationships of potato varieties bred worldwide and in China.
Xiaochuan Li   +9 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Genetic Characterization of Indubrasil Cattle Breed Population

open access: yesVeterinary Sciences, 2018
The Indubrasil breed was developed in the Brazilian region called Triângulo Mineiro as a result of a cross between zebu cattle. Initially, it was used as a terminal cross and currently it represents approximately 4.45% of all the Brazilian zebu ...
Ricardo Zanella   +8 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

The Importance of Marketing in Selling Pedigree Product-group

open access: yes, 2015
Szakdolgozatomban a marketing jelentőségét vizsgáltam a Pedigree termékcsalád értékesítésében. Először szekunder kutatást végeztem, a szakirodalom segítségével áttanulmányoztam milyen marketing eszközök ismeretesek, majd utánajártam, hogy ezen eszközök ...
Nagy, Adrienn
core  

Pedigree-based (FPED), ROH-based (FROH) and microsatellite-based (FMIC) inbreeding coefficients for highly inbred (HI) and outbred (LI) bulls.

open access: yes, 2018
Pedigree-based (FPED), ROH-based (FROH) and microsatellite-based (FMIC) inbreeding coefficients for highly inbred (HI) and outbred (LI) bulls.
Hao Cheng (103394)   +7 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A comparison of founder-only and all-pedigree-members genotype-expression association by regression analysis-0

open access: yes, 2011
Copyright information:Taken from "A comparison of founder-only and all-pedigree-members genotype-expression association by regression analysis"http://www.biomedcentral.com/1753-6561/1/S1/S8BMC Proceedings 2007;1(Suppl 1):S8-S8.Published online 18 Dec ...
Wentian Li (28857)   +3 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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