Results 111 to 120 of about 223,945 (287)

Relationships among quantitative traits in F3, F4 and F5 wheat hybrids obtained by pedigree and bulk selection [PDF]

Selekcija i Semenarstvo, 2010
Relationships among quantitative traits of wheat were analyzed in parents and their F3, F4 and F5 hybrids. Three female parents (Briscard, Carifen 12 and Rescler) were crossed with two male parents (Francuska and PKB-Prelivka). Same crosses were repeated
Janković Snežana, Prodanović Slaven, Ranđelović Violeta   +2 more
doaj  

Pedigree-Based Deciphering of Genome-Wide Conserved Patterns in an Elite Potato Parental Line

Frontiers in Plant Science, 2018
Elite parental lines are more likely to breed fine varieties, but knowledge about elite parents and their genetic backgrounds is limited. In this paper, we investigated the pedigree relationships of potato varieties bred worldwide and in China.
Xiaochuan Li, Xiaochuan Li, Xiaochuan Li, Jianfei Xu, Shaoguang Duan, Chunsong Bian, Jun Hu, Huolin Shen, Guangcun Li, Liping Jin   +9 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Genetic Characterization of Indubrasil Cattle Breed Population

Veterinary Sciences, 2018
The Indubrasil breed was developed in the Brazilian region called Triângulo Mineiro as a result of a cross between zebu cattle. Initially, it was used as a terminal cross and currently it represents approximately 4.45% of all the Brazilian zebu ...
Ricardo Zanella, Luísa V. Lago, Arthur N. da Silva, Fábio Pértille, Nathã S. de Carvalho, João Cláudio do Carmo Panetto, Giovana C. Zanella, Fernanda L. Facioli, Marcos Vinicius G.B. da Silva   +8 more
doaj   +1 more source

Effective Sample Size: Quick Estimation of the Effect of Related Samples in Genetic Case-Control Association Analyses [PDF]

, 2007
Correlated samples have been frequently avoided in case-control genetic association studies in part because the methods for handling them are either not easily implemented or not widely known.
Chukwuma Ogunwole, Daniel Kastner, Elaine L. Remmers, Peter K. Gregersen, Wentian F. Li, Yaning B. Yang   +5 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Genomic selection in oil palm (Elaeis guineensis Jacq.) [PDF]

, 2014
Genomic selection (GS) can increase the genetic gain in plants. In perennial crops, this can be achieved via shortened breeding cycles and increased selection intensity. Our objective was to obtain the first empirical estimate of GS accuracy in oil palm (
Bouvet, Jean-Marc, Cochard, Benoît, Cros, David, Denis, Marie, Durand-Gasselin, Tristan, Flori, Albert, Nouy, Bruno, Omoré, Alphonse, Pomies, Virginie, Riou, Virginie, Sanchez, Leopoldo, Suryana, Edyana   +11 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source