Results 111 to 120 of about 9,370 (221)

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science, EarlyView.
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
wiley   +1 more source

Whole-Genome Data to Investigate Recent and Historical Dog Introgression Patterns in Italian Wolves. [PDF]

Ecol Evol
Battilani D, Ramos Madrigal J, Hennelly LM, Gopalakrishnan S, Vernesi C, Mattucci F, Fabbri E, Ciucci P, Caniglia R.   +8 more
europepmc   +1 more source

What's Scientific About Forensic Science? Three Versions of American Forensics, 1903-1965, and One Modest Proposal. [PDF]

Acad Forensic Pathol, 2021
Hamlin C.
europepmc   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

Evaluation of the Prevalence of Genetic Variants at the Nebulette Locus in Cavalier King Charles Spaniels. [PDF]

Animals (Basel)
Melis C, Wade C, Rozendom C, van Steenbeek FG, Beijerink NJ.   +4 more
europepmc   +1 more source

Genetic characteristics of Korean Jeju Black cattle with high density single nucleotide polymorphisms. [PDF]

Anim Biosci, 2021
Alam MZ, Lee YM, Son HJ, Hanna LH, Riley DG, Mannen H, Sasazaki S, Park SP, Kim JJ.   +8 more
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Genomic prediction and genome-wide association studies of morphological traits and distraction index in Korean Sapsaree dogs. [PDF]

PLoS One
Haque MA, Kim NK, Yeji R, Lee B, Ha JH, Lee YM, Kim JJ.   +6 more
europepmc   +1 more source

Split-screen visions: Heracles on top of Troy in the Casa di Octavius Quartio in Pompeii [PDF]

, 2013
Lorenz, Katharina
core   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source