Results 111 to 120 of about 9,370 (218)

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Whole-Genome Data to Investigate Recent and Historical Dog Introgression Patterns in Italian Wolves. [PDF]

Ecol Evol
Battilani D, Ramos Madrigal J, Hennelly LM, Gopalakrishnan S, Vernesi C, Mattucci F, Fabbri E, Ciucci P, Caniglia R.   +8 more
europepmc   +1 more source

Sensory Nerve‐Derived CGRP Controls Osteoclastogenesis by Limiting Macrophage Bioenergetics in Bone Repair

Advanced Science, EarlyView.
Sensory nerves help bones heal. This study shows that the neuropeptide CGRP, released from sensory nerves, slows down macrophage energy production, preventing excessive bone breakdown. By revealing this nerve–immune–metabolism connection, the work provides new insight into how the body balances bone repair and opens doors to targeted treatments ...
Jiaying Liu, Ting Zhang, Yuqing Mu, Lili Li, Ju Jin, Kevin J Dudley, Wendong Gao, Donglin Cai, Fuhua Yan, Lan Xiao, Yin Xiao   +10 more
wiley   +1 more source

Evaluation of the Prevalence of Genetic Variants at the Nebulette Locus in Cavalier King Charles Spaniels. [PDF]

Animals (Basel)
Melis C, Wade C, Rozendom C, van Steenbeek FG, Beijerink NJ.   +4 more
europepmc   +1 more source

What's Scientific About Forensic Science? Three Versions of American Forensics, 1903-1965, and One Modest Proposal. [PDF]

Acad Forensic Pathol, 2021
Hamlin C.
europepmc   +1 more source

A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects

Advanced Science, EarlyView.
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi, Nian Liu, Jingyi Gu, Yinling Wang, Weiye Wang, Zhiwei Ke, Mingjun Xie, Wenjing Jin, Weicheng Kong, Jue Shi, Hui Pan, Yong He, Zhijian Xie   +12 more
wiley   +1 more source

Genomic prediction and genome-wide association studies of morphological traits and distraction index in Korean Sapsaree dogs. [PDF]

PLoS One
Haque MA, Kim NK, Yeji R, Lee B, Ha JH, Lee YM, Kim JJ.   +6 more
europepmc   +1 more source

Genomic signatures and evolutionary history of the endangered blue-crowned laughingthrush and other Garrulax species. [PDF]

BMC Biol, 2022
Chen H, Huang M, Liu D, Tang H, Zheng S, Ouyang J, Zhang H, Wang L, Luo K, Gao Y, Wu Y, Wu Y, Xiong Y, Luo T, Huang Y, Xiong R, Ren J, Huang J, Yan X.   +18 more
europepmc   +1 more source

Split-screen visions: Heracles on top of Troy in the Casa di Octavius Quartio in Pompeii [PDF]

, 2013
Lorenz, Katharina
core   +1 more source

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

Advanced Science, EarlyView.
Constitutive PRKCN expression is driven by super‐enhancers and modulated by NF‐κB signaling in multiple myeloma (MM). PRKCN activates mTORC1/2‐IRF4 signaling axis and favors tumor cell growth independently of its kinase activity. IRF4 reciprocally promotes PRKCN transcription, creating a feed‐forward loop.
Koukou Tang, Dongpeng Jiang, Peng Ke, Xiaosen Bian, Lili Zhang, Ying Zhang, Tingting Zhu, Weiwei Qu, Wenhui Qi, Yang Xu, Chengcheng Fu, Depei Wu, Jianhong Chu   +12 more
wiley   +1 more source