Results 131 to 140 of about 9,370 (218)

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

Advanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang, Yaodong Gu, Wen Du, Lin Xie, Jinwei Quan, Yu Zhao, Ye Cheng, Zhaonan Wei, Yuanyuan Sha, Yi Wang, Dechao Xu, Xiang Gao, Min Chen, Xiangchen Gu   +13 more
wiley   +1 more source

First Detection of Bluetongue Virus Type 3 in Poland in 2024-A Case Study in European Bison (<i>Bison bonasus</i>). [PDF]

Pathogens
Larska M, Orłowska A, Łopuszyński W, Skurka Ł, Nowakowska A, Trębas P, Krzysiak MK, Rola J, Smreczak M.   +8 more
europepmc   +1 more source

Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes.

Curr Biol, 2021
Yaka R, Mapelli I, Kaptan D, Doğu A, Chyleński M, Erdal ÖD, Koptekin D, Vural KB, Bayliss A, Mazzucato C, Fer E, Çokoğlu SS, Lagerholm VK, Krzewińska M, Karamurat C, Gemici HC, Sevkar A, Dağtaş ND, Kılınç GM, Adams D, Munters AR, Sağlıcan E, Milella M, Schotsmans EMJ, Yurtman E, Çetin M, Yorulmaz S, Altınışık NE, Ghalichi A, Juras A, Bilgin CC, Günther T, Storå J, Jakobsson M, de Kleijn M, Mustafaoğlu G, Fairbairn A, Pearson J, Togan İ, Kayacan N, Marciniak A, Larsen CS, Hodder I, Atakuman Ç, Pilloud M, Sürer E, Gerritsen F, Özbal R, Baird D, Erdal YS, Duru G, Özbaşaran M, Haddow SD, Knüsel CJ, Götherström A, Özer F, Somel M.   +56 more
europepmc   +1 more source

Inactivation Rap2a in Endothelial Cell Prevents Pulmonary Fibrosis by Regulating Immune Microenvironment Through MAP4K4‐VCAM1 Signaling

Advanced Science, EarlyView.
We identified the endothelial RAP2A as a regulator of inflammatory endothelial activation in experimental lung fibrosis and suggest that targeting RAP2A‐mediated signaling may represent a potential strategy to modulate endothelial–immune crosstalk during fibrotic lung injury.
Xiaolan Zheng, Peng Yue, Kaiyu Zhou, Guidong Gong, Yue Zhang, Sha Lin, Xu Liu, Yanjiang Zheng, Siyuan Jing, Junling Guo, Yan Qi, Bi‐Sen Ding, Yimin Hua, Yifei Li   +13 more
wiley   +1 more source

The importance of geographic and sociodemographic aspects in the characterization of mucopolysaccharidoses: a case series from Ceará state (Northeast Brazil). [PDF]

J Community Genet
Cardoso-Dos-Santos AC, Mariath LM, Trapp F, Facchin ACB, Leistner S, Kubaski F, Giugliani R, Schuler-Faccini L, Ribeiro EM.   +8 more
europepmc   +1 more source

A de novo frameshift mutation in ZEB2 causes polledness, abnormal skull shape, small body stature and subfertility in Fleckvieh cattle. [PDF]

Sci Rep, 2020
Gehrke LJ, Upadhyay M, Heidrich K, Kunz E, Klaus-Halla D, Weber F, Zerbe H, Seichter D, Graf A, Krebs S, Blum H, Capitan A, Thaller G, Medugorac I.   +13 more
europepmc   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

Advanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou, Danfeng Cai, Changbin Zhao, Siyu Zhang, Jiahao Li, Zhaofeng Zhang, Shaofen Kong, Xin Yang, Xiaoli Zhou, Farhad Bordbar, Fayi Chen, Yaohuan Xu, Zhe Zhang, Lihong Gu, Zhenhui Li, Xiquan Zhang, Wen Luo, Jingting Shu, Bolin Cai, Qinghua Nie   +19 more
wiley   +1 more source

Mapping Plastic and Plastic Additive Cycles in Coastal Countries: A Norwegian Case Study. [PDF]

Environ Sci Technol
Marhoon A, Hernandez MLH, Billy RG, Müller DB, Verones F.   +4 more
europepmc   +1 more source

From the Eurasian Steppes to the Roman Circuses: A Review of Early Development of Horse Breeding and Management. [PDF]

Animals (Basel), 2021
Klecel W, Martyniuk E.
europepmc   +1 more source