Results 61 to 70 of about 9,313 (188)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1268-1275, June 2026.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Comparison of the EQ-5D-Y-5L, EQ-5D-Y-3L and PedsQL in children and adolescents

, 2022
BACKGROUND: There is an increased use of Patient-Reported Outcome Measures (PROMs) in children and adolescents. The aim of this study was to compare the feasibility, concurrent validity and known-group validity of the EQ-5D-Y-3L (Y-3L), EQ-5D-Y-5L (Y-5L)
Verstraete, Janine, Scott, Des
core   +1 more source

Evaluating Brief Behavioural Activation for depression in adolescents with acquired brain injury using a single‐case experimental design

JCPP Advances, Volume 6, Issue 2, June 2026.
Abstract Background Adolescents who have had an acquired brain injury (ABI) commonly experience depression. Brief Behavioural Activation (Brief BA) is a successful, values‐based intervention for managing depression in neurotypical adolescents. This study investigated the effectiveness of Brief BA, using a single‐case experimental design, with ...
Conor R. O’Brien, Jenny Limond, Shirley Reynolds, Laura Pass, Anna‐Lynne R. Adlam   +4 more
wiley   +1 more source

PedsQL Sağlık Bakımı Ebeveyn Memnuniyet Ölçeğinin Türkçe’ye Uyarlanması

, 2012
ÖZET Amaç: Bu araştırma, “PedsQL Sağlık Bakımı Memnuniyet Ölçeği”nin geçerlik ve güvenirliğinin yapılması amacı ile planlanmıştır. Yöntem: Bu çalışma metodolojik niteliktedir.
Kublay, Gülümser, Ulus, Bahire
core  

Association of Weight Status and Quality of Life Through Childhood and Adolescence: Australian Longitudinal Cohort Analysis

Obesity, Volume 34, Issue 6, Page 1314-1321, June 2026.
ABSTRACT Objective This study examined the relationship between health‐related quality of life (HRQoL) and weight status across the pediatric life course. Methods We analyzed data from a cohort of 9745 children from the Longitudinal Study of Australian Children, with follow‐up over 14 years.
Alison Hayes, Thomas Lung, Kirsten Howard, Louise Baur, Anagha Killedar   +4 more
wiley   +1 more source

Home‐Based Versus In‐Hospital Care in Pediatrics: A Systematic Review of Cost‐Effectiveness Studies

World Medical &Health Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Home‐based care has emerged as a potential alternative to traditional hospital‐based care for children and adolescents worldwide. This systematic review aimed to systematically gather and critically assess the available evidence on the cost‐effectiveness of home‐based versus in‐hospital care for pediatric populations globally.
Luís Carlos Lopes‐Júnior, Raphael Manhães Pessanha, Wesley Rocha Grippa, Jonathan Grassi, Luiz Cláudio Barreto Silva Neto, Mariana Rabello Laignier, María Liliana Vásquez Ponce, Karla Anacleto de Vasconcelos, Regina Aparecida Garcia de Lima   +8 more
wiley   +1 more source

Adaptación y validación del instrumento PedsQL 4.0™ (Pediatric Quality of Life Inventory) para la medición pediátrica de la calidad de vida relacionada con la salud, en colombianos menores de edad

El instrumento Pediatric Quality of Life Inventory (PedsQL) creado por Varni y sus colaboradores en Estados Unidos. es una herramienta que fue creada con el objetivo de realizar una evaluación genérica que mida sistemáticamente la calidad de vida de ...
Eslava Schmalbach, Javier Hernando
core   +1 more source

Participation, environment, and quality of life in children with cerebral palsy and physical disabilities

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 800-809, June 2026.
Abstract Aim To compare and examine relationships between participation, environmental factors, and quality of life (QoL) in children with cerebral palsy and physical disability (CP/PD) and typically developing children. Method Participants were 59 children (6–12 years; 31 females): 30 with CP/PD (mean age 8 years 7 months, standard deviation 1 year 6 ...
Nava Gelkop, Batya Engel‐Yeger
wiley   +1 more source

Co‐Creation of a Study Protocol to Assess the Effect of Transcranial Direct Current Stimulation in the Management of Fatigue in Children and Young People With Acquired Brain Injury (Fatiguebrain‐tDCS)

Health Expectations, Volume 29, Issue 3, June 2026.
ABSTRACT Background Children and young people (CYP) with moderate/severe acquired brain injury (ABI) often have problems with chronic cognitive fatigue. Methylphenidate, a controlled drug, and cognitive behavioural therapy have been used to manage fatigue, but their effects are not fully established, and they are not widely available.
Chandrasekar Rathinam, Gemma Heath, Rajat Gupta, Evangeline Wassmer, Emily McElroy, Helen Horn, Davinia Fernandez‐Espejo   +6 more
wiley   +1 more source

PedsQL for Prediction of Postoperative Patient-Reported Outcomes following Chiari Decompression Surgery

, 2019
Background and Hypothesis: Chiari malformation type I (CM-I) is a common pediatric disorder in which the cerebellar tonsils herniate the foramen magnum with associated spinal symptoms.
Zieles,BS, Kristin, Baygani, BS, Shawyon, Jea, MD, MHA, Andrew   +2 more
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