Results 101 to 110 of about 1,496,607 (316)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

A review of peer-to-peer transaction loss and blockchain: challenges and drivers in the roadmap to a low-carbon future

Frontiers in Energy Research
Adapting to horizontal market structures faces several drivers and challenges in the context of sustainable energy transition. The inherently decentralized nature qualifies blockchain technology as the major technical driver in the transition to peer-to ...
Maya P, P. Abdul Salam
doaj   +1 more source

Peer relations linking overweight and obesity, and mediator factors among Turkish adolescents

, 2022
Başak Koca Özer, Müdriye Yıldız Bıçakçı, Hakkı Okan Yeloğlu, Neriman Aral, Ayşegül Özdemir Başaran, Cansev Meşe Yavuz, Sibel Önal, Ece Özdoğan Özbal, Sebahat Aydos   +8 more
openalex   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Role of Technical Car Features in Managing and Promoting New Peer-to-Peer Car-Sharing Systems: Insights from Potential Users and Strategic Implications for Service Providers

Applied Sciences
Peer-to-peer car-sharing systems are an evolving branch of urban mobility, aligning with global trends focused on sustainable development and reducing congestion in cities.
Katarzyna Turoń, Andrzej Kubik, Piotr Folęga, Andrzej Wilk, Peter Bindzar, Truong M. N. Bui   +5 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Peer-to-Peer säkerhet [PDF]

, 2016
Arbetets område är Peer-to-Peer säkerhet och baserar sig på litteraturstudier. Ett Peer-to-Peer nätverk är ett datornätverk av sammankopplade noder som inte följer klient-server modellen. Noderna i nätverket kan agera i alla roller, vilket leder till att
Gustafsson, Kasper
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Peer-to-Peer EnergyTrade: A Distributed Private Energy Trading Platform

, 2018
Blockchain is increasingly being used as a distributed, anonymous, trustless framework for energy trading in smart grids. However, most of the existing solutions suffer from reliance on Trusted Third Parties (TTP), lack of privacy, and traffic and ...
Dong, Zhao Yang, Dorri, Ali, Hill, Ambrose, Jurdak, Raja, Kanhere, Salil S, Luo, Fengji   +5 more
core   +1 more source