Results 81 to 90 of about 87,991,808 (290)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Rise and Fall of the Peer-to-Peer Empire
Tsinghua Science and Technology, 2012 The essence of the peer-to-peer design philosophy is to design protocols for end hosts, or "peers", to work in collaboration to achieve a certain design objective, such as the sharing of a large file.
Baochun Li, Yuan Feng, Bo Li
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Whether you are new to mentoring or looking to refine your skills, this guide will cover the essentials of effective communication, why peer support matters, and how you can build inclusive and meaningful relationships with the students you ...
Peer Mentoring team
core +1 more source
Efficient and Effective Use of Peer Teaching for Medical Student Simulation
Western Journal of Emergency Medicine, 2017 Simulation is increasingly used in medical education, promoting active learning and retention; however, increasing use also requires considerable instructor resources.
House, Joseph +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Applied SciencesPeer-to-peer car-sharing systems are an evolving branch of urban mobility, aligning with global trends focused on sustainable development and reducing congestion in cities.
Katarzyna Turoń +5 more
doaj +1 more source
Peer-Assisted Information-Centric Network (PICN): A Backward Compatible Solution
IEEE Access, 2017 Information-centric networking (ICN) is a promising solution for most of Internet applications where the content represents the core of the application.
Zeinab Zali +4 more
doaj +1 more source
Peer-to-Peer Semantic Wikis [PDF]
, 2009 This paper presents SWOOKI the first peer-to-peer semantic wiki. A P2P semantic wiki combines advantages of both semantic wikis and P2P Wikis. A P2P semantic wiki network is composed of a set of interconnected autonomous servers that can dynamically join and leave the network.
Skaf, Hala +2 more
openaire +4 more sources