Results 151 to 160 of about 1,114,725 (266)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Peer-to-Peer Mental Health Training: A National Model for Peer Support for Medical and Dental Students. [PDF]

MedEdPORTAL
Amini A, Rami A, Teng RW, Baselga-Garriga C, Esmail K, Raza M, Oles W, Cerda IH, Czeisler MÉ, Sander MT, Wang V, Pulukuri S, Abramson D, Saldaña F, Potter J.   +14 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Impact of Physician Storytelling and Peer-to-Peer Conversation on Medical Students' Coping Skills and Anticipatory Fear Surrounding Patient Death: A Pre-post Cohort Study. [PDF]

Cureus
Koh S, Ohno Y, Khan H.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Strengthening the cognition of university students to refuse e-cigarette use: A pilot randomized controlled trial of a peer-to-peer intervention. [PDF]

Tob Induc Dis
Chen Y, Lin S, Lin H, Wang Z, Zhao X, Ao P, Cai Y, Xu J, Yu X, Yang X, Chan KS.   +10 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

"Just realising that I wasn't alone… was profound": a mixed-methods evaluation of a pilot peer-to-peer wellbeing program for carers of children with rare epilepsies. [PDF]

Orphanet J Rare Dis
Pierce K, Murphy JB, Robertson EG, Khan JR, Bullock S, O'Loughlin CB, Loden M, McIntosh R, Beavis E, Roberts N, Palmer EE, Lingam R.   +11 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Peer-to-Peer Support in a Suicidal Crisis: Comparing Traditional in-Person Training With Virtual Reality (VR) Training Among United States Air Force Personnel. [PDF]

Omega (Westport)
Robison M, Prostko S, Jones V, Joiner TE.   +3 more
europepmc   +1 more source