Results 51 to 60 of about 1,674,089 (232)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Associations Between Attachment Security and Social Competence in Preschool Children [PDF]
, 2014 Attachment theorists suggest that attachment security with parents supports the quality of social adaptation in peer groups during early childhood, and numerous studies supporting this conjecture have been published.
Santos, António José +13 more
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Hostile attributional style, mentalisation and attachment in preadolescence. [PDF]
, 2005 This review aims to explore social information processing styles, mentalisation abilities, and attachment security, and their associations, in relation to aggressive behaviours.
Nelson, L.
core
Group identity and peer relations: A longitudinal study of group identity, perceived peer acceptance and friendships amongst ethnic minority English children [PDF]
, 2011 This research examined whether peer relationships amongst ethnic minority status children reflect the social groups to which children belong and the degree to which they identify with these groups.
Anick Landau (16053803) +38 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Revista Crítica de Ciências Sociais, 2019 A secure peer attachment appears in the literature as a protective factor against bullying behavior. The present study seeks to test the predictor effect of peer attachment on different types of bullying and to examine the mediating role of gender on the
Denise Dias +2 more
doaj
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Peer Involvement in University Students' Education [PDF]
Revija za Elementarno Izobraževanje, 2016 We investigated the correlations between peer involvement in students’ education and their self-perception, attachment style, relationships with peers, personality and well-being.
Zlatka Cugmas, Eva Kranjec
doaj
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source